biostudies-literatureDwyer DECCR NIH HHSNIAID NIH HHSMedical Research CouncilNational Cancer InstituteNCI NIH HHSNational Institutes of Healthofx212https://www.ebi.ac.uk/biostudies/studies/S-EPMC5740982biostudies-literatureUnknown4(4)<h4>Background</h4>Outcome data from prospective follow-up studies comparing infections with different influenza virus types/subtypes are limited.<h4>Methods</h4>Demographic, clinical characteristics and follow-up outcomes for adults with laboratory-confirmed influenza A(H1N1)pdm09, A(H3N2), or B virus infections were compared in 2 prospective cohorts enrolled globally from 2009 through 2015. Logistic regression was used to compare outcomes among influenza virus type/subtypes.<h4>Results</h4>Of 3952 outpatients, 1290 (32.6%) had A(H1N1)pdm09 virus infection, 1857 (47.0%) had A(H3N2), and 805 (20.4%) had influenza B. Of 1398 inpatients, 641 (45.8%) had A(H1N1)pdm09, 532 (38.1%) had A(H3N2), and 225 (16.1%) had influenza B. Outpatients with A(H1N1)pdm09 were younger with fewer comorbidities Open forum infectious diseasesComparison of the Outcomes of Individuals With Medically Attended Influenza A and B Virus Infections Enrolled in 2 International Cohort Studies Over a 6-Year Period: 2009-2015.PMC5740982UOI-AI068641MC_UU_12023/22HHSN261200800001EHHSN261200800001CFLU002U01 AI068641FLU003Pett SRam RKoletar SMetcalf JBelloso WBabiker ABach KFlorence EWolfe CRMulle HBielen MGutierrez LBrekke KGunter JLipari FSchurmann DSans Moreno JLa Rosa ACunningham NStephan CLundgren Jde Paz Sierra MYahni DRussell CMunroe DDavid DMartinez MLTedaldi EBorges AHDNovak RJeffs BCornelio EWu TCMcLaughlin KDeHovitz JAKantzanou MLee Bertrand MStoehr ABarcelona LBrockmeyer NKummerle TKnobel HGeorge MCastillo RTouloumi GRamon Pano JJansson POBallesteros MFLopez PVieni IKowalska KPSchwarber MGarlick JCozzi-Lepri AImamura JSchooley RDaikos GMykietiuk AIwatani YSivoravong JOestergaard LStauning Pedersen JAWebb HBogner JRCoburn PCourtney-Rodgers DMacArthur RKoratzanis GBraimah NGreen JJoensen ZMVincent TWentworth DSondengam RSkoutelis AManosuthi WKilkenny FKoerbel GPearson MRichmond SCrinejo AWiebecke SDassow PGrenade JMuller VNahra REbenrstejin JAnagnostou OReilly NASanchez-Sendin DBaker JVKlinker HPeters LBarcan LParker SKutter SLopardo AMeng Soo TDenning EGunderson EHoover MRuxrungtham KWolff MDemocratis JNelson RVjecha MPutcharoen OAllendes GFlores JDalmau DUddin DEBeigel JLopardo GSugiura WLynfield RZilmer KZarate AHMinton JPortas BJohnson MZubkiewicz-Zarebska AAtkinson BRizza STemesgen ZGlesby MNewport MRockstroh JTemporiti EJo Garrett KJeppesen MScott JRodrigo MPedersen RKSimon GLNakahata MHidalgo JVoell JE Schmidt WPerez CNatarajan VNielsen HCisneros VPaez-Quinde MHabel PRomero PAguila DSaenz MPlettenberg AMaltezos ECollins PThron BWolf TSeybold UHergens LProne IMoore RPedersen CHorban AJTraverse CCarbone JGover EAulicino TMLosso MLaopraynak NMcConnell RCharoentonpuban KBennett RFernandez Cruz EHerrero PBeilke MBardascino CBenites CSanchez PVasilopoulos NEmery SClark LGioukari VLan AHughes VAndry LArduino RPolenakovik HFaber LSkiest DJSanchez MCaeiro JPWarley EHurt CBaxter JLoftheim IRFarrough MKronborg GKnysz BArribas JChinchay RLehmann CDewar RRehman TEdwards SCzaja-Harder Cde Tesco AMPolixronopoulos VFatkenheuer GQvist TDharan NJBerdinas VWeckx JPeroni LBergmann FKogure APaez APVaughan WMTavella SNeaton JDGuevara MSchlabe SRoth NTillmann KMacRae KMaagaard AAlzogaray MFBaxter JDThomas DSuwanpimonkul GBass CNuffer KBonvehi PTobudic SShaw PVega JYehdego YDuChene AMontejano RBaadegaard BStandridge BRiska PFDoldan LGardner EDraenert RPowell SChetchotisakd PLucchetti PQuan SFCarbonneau JJo-Anne TNettles MJJensen LPSanchez ACursley ASwanson NDavey RTVelasco IHudson FTrape LPrice ADwyer DEVlakahis EWoolstencroft RChu MYWatson VElliott JKok JClarke TProsser RAChadwick DWatson KMarcus CAntoniadou APatil NCohen CJINSIGHT Influenza Study GroupFreiberg MKalomenidis IHolman SPinedo YDockrell DUbolyam SEid MCarey DImahashi MHeyderman RCindrich RWade BKaewon PKoulouris NHam KAagaard BGerstoft JNielsen BRUslan DZMarkowitz NVasco MMetallidis SCollaco-Moraes YOmotosho BGordin FNieto LGeisler COlivet HBEngen NBurgmann HLupo SSchuttfort GSchultz TNieto GSambatakou HSoriano VBrown ABHarrison MWalker CSagaer JKabeya KRodriguez PLosso MHNannini ESolorzano CNixon DWohl DNorthland RClumeck NRetta IBloch MMcBride JBoesecke CCampbell MEstrada VLau HAngus BPussadee KLlewelyn MUyeki TMCummins SVecino IKase KBakowska EMacias LMAvihingsanon ABrown SBentley BDYokomaku YfalseComparison of the Outcomes of Individuals With Medically Attended Influenza A and B Virus Infections Enrolled in 2 International Cohort Studies Over a 6-Year Period: 2009-2015.<h4>Background</h4>Outcome data from prospective follow-up studies comparing infections with different influenza virus types/subtypes are limited.<h4>Methods</h4>Demographic, clinical characteristics and follow-up outcomes for adults with laboratory-confirmed influenza A(H1N1)pdm09, A(H3N2), or B virus infections were compared in 2 prospective cohorts enrolled globally from 2009 through 2015. Logistic regression was used to compare outcomes among influenza virus type/subtypes.<h4>Results</h4>Of 3952 outpatients, 1290 (32.6%) had A(H1N1)pdm09 virus infection, 1857 (47.0%) had A(H3N2), and 805 (20.4%) had influenza B. Of 1398 inpatients, 641 (45.8%) had A(H1N1)pdm09, 532 (38.1%) had A(H3N2), and 225 (16.1%) had influenza B. Outpatients with A(H1N1)pdm09 were younger with fewer comorbidities 2017-01-01T00:00:00Z20172026-05-01T07:23:21.7Z2019-03-27T03:05:38ZS-EPMC57409822930840110.1093/ofid/ofx212