{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Santos EMM"],"funding":["Stichting voor de Technische Wetenschappen","ITEA3"],"pagination":["71-79"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5748434"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["60(1)"],"pubmed_abstract":["<h4>Purpose</h4>Thrombus perviousness has been associated with favorable functional outcome in acute ischemic stroke (AIS) patients. Measuring thrombus perviousness on CTA may be suboptimal due to potential delay in contrast agent arrival in occluded arteries at the moment of imaging. Dynamic sequences acquired over time can potentially overcome this issue. We investigate if dynamic CTA has added value in assessing thrombus perviousness.<h4>Methods</h4>Prospectively collected image data of AIS patients with proven occlusion of the anterior or posterior circulation with thin-slice multi-phase CTA (MCTA) and non-contrast CT were co-registered (n = 221). Thrombus attenuation increase (TAI; a perviousness measure) was measured for the arterial, venous, and delayed phase of the MCTA and time-in"],"journal":["Neuroradiology"],"pubmed_title":["Added value of multiphase CTA imaging for thrombus perviousness assessment."],"pmcid":["PMC5748434"],"funding_grant_id":["10004","11632"],"pubmed_authors":["Najm M","Demchuk AM","Santos EMM","Zini A","Menon BK","Marquering HA","Majoie CB","Goyal M","PRove-IT investigators","Treurniet KM","Mandzia J","Niessen WJ","Shankar JJ","Khaw AV","Fainardi E","d'Esterre CD","Rubiera M"],"additional_accession":[]},"is_claimable":false,"name":"Added value of multiphase CTA imaging for thrombus perviousness assessment.","description":"<h4>Purpose</h4>Thrombus perviousness has been associated with favorable functional outcome in acute ischemic stroke (AIS) patients. Measuring thrombus perviousness on CTA may be suboptimal due to potential delay in contrast agent arrival in occluded arteries at the moment of imaging. Dynamic sequences acquired over time can potentially overcome this issue. We investigate if dynamic CTA has added value in assessing thrombus perviousness.<h4>Methods</h4>Prospectively collected image data of AIS patients with proven occlusion of the anterior or posterior circulation with thin-slice multi-phase CTA (MCTA) and non-contrast CT were co-registered (n = 221). Thrombus attenuation increase (TAI; a perviousness measure) was measured for the arterial, venous, and delayed phase of the MCTA and time-in","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jan","modification":"2025-04-19T12:32:50.982Z","creation":"2019-03-27T03:06:03Z"},"accession":"S-EPMC5748434","cross_references":{"pubmed":["28963573"],"doi":["10.1007/s00234-017-1907-y"]}}