{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Muehe AM"],"funding":["Eunice Kennedy Shriver National Institute of Child Health and Human Development","NICHD NIH HHS"],"pagination":["324-335"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5773418"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(2)"],"pubmed_abstract":["<h4>Purpose</h4>To provide clinically useful gadolinium-free whole-body cancer staging of children and young adults with integrated positron emission tomography/magnetic resonance (PET/MR) imaging in less than 1 h.<h4>Procedures</h4>In this prospective clinical trial, 20 children and young adults (11-30 years old, 6 male, 14 female) with solid tumors underwent 2-deoxy-2-[<sup>18</sup>F]fluoro-D-glucose ([<sup>18</sup>F]FDG) PET/MR on a 3T PET/MR scanner after intravenous injection of ferumoxytol (5 mg Fe/kg) and [<sup>18</sup>F]FDG (2-3 MBq/kg). Time needed for patient preparation, PET/MR image acquisition, and data processing was compared before (n = 5) and after (n = 15) time-saving interventions, using a Wilcoxon test. The ferumoxytol-enhanced PET/MR images were compared with clinical s"],"journal":["Molecular imaging and biology"],"pubmed_title":["How to Provide Gadolinium-Free PET/MR Cancer Staging of Children and Young Adults in Less than 1 h: the Stanford Approach."],"pmcid":["PMC5773418"],"funding_grant_id":["R01 HD081123","R01 HD081123-01A1"],"pubmed_authors":["Theruvath AJ","Aghighi M","Marina N","Muehe AM","Luna-Fineman S","Quon A","Holdsworth SJ","Advani R","Rosenberg J","Lai L","Wang J","Daldrup-Link HE"],"additional_accession":[]},"is_claimable":false,"name":"How to Provide Gadolinium-Free PET/MR Cancer Staging of Children and Young Adults in Less than 1 h: the Stanford Approach.","description":"<h4>Purpose</h4>To provide clinically useful gadolinium-free whole-body cancer staging of children and young adults with integrated positron emission tomography/magnetic resonance (PET/MR) imaging in less than 1 h.<h4>Procedures</h4>In this prospective clinical trial, 20 children and young adults (11-30 years old, 6 male, 14 female) with solid tumors underwent 2-deoxy-2-[<sup>18</sup>F]fluoro-D-glucose ([<sup>18</sup>F]FDG) PET/MR on a 3T PET/MR scanner after intravenous injection of ferumoxytol (5 mg Fe/kg) and [<sup>18</sup>F]FDG (2-3 MBq/kg). Time needed for patient preparation, PET/MR image acquisition, and data processing was compared before (n = 5) and after (n = 15) time-saving interventions, using a Wilcoxon test. The ferumoxytol-enhanced PET/MR images were compared with clinical s","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Apr","modification":"2025-04-04T20:43:41.958Z","creation":"2019-08-04T08:21:18Z"},"accession":"S-EPMC5773418","cross_references":{"pubmed":["28721605"],"doi":["10.1007/s11307-017-1105-7"]}}