{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kurnit KC"],"funding":["NCATS","NCATS NIH HHS","NCI NIH HHS","NIH","Cancer Prevention and Research Institute of Texas","MD Anderson Cancer Center"],"pagination":["e123-e126"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5774617"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["77(21)"],"pubmed_abstract":["High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to guide cancer patient care, especially in advanced and incurable cancers. However, navigating the scientific literature to make evidence-based clinical decisions based on molecular profiling results is overwhelming for many oncology clinicians and researchers. The Personalized Cancer Therapy website (www.personalizedcancertherapy.org) was created to provide an online resource for clinicians and researchers to facilitate navigation of available data. Specifically, this resource can be used to help identify potential therapy options for patients harboring oncogenic genomic alterations. Herein, we describe how content on www.personalizedcancertherapy.org is generated and maintained. We end with case scenarios to illustrate the clinical utility of the website. The goal of this publicly available resource is to provide easily accessible information to a broad oncology audience, as this may help ease the information retrieval burden facing participants in the precision oncology field. <i>Cancer Res; 77(21); e123-6. ©2017 AACR</i>."],"journal":["Cancer research"],"pubmed_title":["\"Personalized Cancer Therapy\": A Publicly Available Precision Oncology Resource."],"pmcid":["PMC5774617"],"funding_grant_id":["T32 CA101642","U01 CA180964","UL1 TR000371","P30 CA016672","RP150535","1U01 CA180964"],"pubmed_authors":["Simpson A","Bailey AM","Bernstam E","Meric-Bernstam F","Kurnit KC","Shufean MA","Sanchez NS","Mendelsohn J","Litzenburger BC","Khotskaya YB","Zeng J","Brusco L","Mills GB","Johnson AM","Holla V","Shaw K"],"additional_accession":[]},"is_claimable":false,"name":"\"Personalized Cancer Therapy\": A Publicly Available Precision Oncology Resource.","description":"High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to guide cancer patient care, especially in advanced and incurable cancers. However, navigating the scientific literature to make evidence-based clinical decisions based on molecular profiling results is overwhelming for many oncology clinicians and researchers. The Personalized Cancer Therapy website (www.personalizedcancertherapy.org) was created to provide an online resource for clinicians and researchers to facilitate navigation of available data. Specifically, this resource can be used to help identify potential therapy options for patients harboring oncogenic genomic alterations. Herein, we describe how content on www.personalizedcancertherapy.org is generated and maintained. We end with case scenarios to illustrate the clinical utility of the website. The goal of this publicly available resource is to provide easily accessible information to a broad oncology audience, as this may help ease the information retrieval burden facing participants in the precision oncology field. <i>Cancer Res; 77(21); e123-6. ©2017 AACR</i>.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Nov","modification":"2025-04-04T11:32:05.834Z","creation":"2019-03-27T00:05:02Z"},"accession":"S-EPMC5774617","cross_references":{"pubmed":["29092956"],"doi":["10.1158/0008-5472.can-17-0341","10.1158/0008-5472.CAN-17-0341"]}}