biostudies-literatureEriksson JSVetenskapsrådetStiftelserna Wilhelm och Martina LundgrensEuropean Research CouncilKungliga Fysiografiska Sällskapet i LundStiftelsen Lars Hiertas MinneRoyal Swedish Academy of SciencesStiftelsen för Strategisk ForskningKnut och Alice Wallenbergs StiftelseHelge Ax:son Johnsons Stiftelse9https://www.ebi.ac.uk/biostudies/studies/S-EPMC5787288biostudies-literatureUnknown18(1)<h4>Background</h4>Whole genome duplication plays a central role in plant evolution. There are two main classes of polyploid formation: autopolyploids which arise within one species by doubling of similar homologous genomes; in contrast, allopolyploidy (hybrid polyploidy) arise via hybridization and subsequent doubling of nonhomologous (homoeologous) genomes. The distinction between polyploid origins can be made using gene phylogenies, if alleles from each genome can be correctly retrieved. We examined whether two closely related tetraploid Mediterranean shrubs (Medicago arborea and M. strasseri) have an allopolyploid origin - a question that has remained unsolved despite substantial previous research. We sequenced and analyzed ten low-copy nuclear genes from these and related species, phaBMC evolutionary biologyAllele phasing is critical to revealing a shared allopolyploid origin of Medicago arborea and M. strasseri (Fabaceae).PMC57872882009-5206331024Bertrand YJKde Sousa FOxelman BEriksson JSAntonelli APfeil BEfalseAllele phasing is critical to revealing a shared allopolyploid origin of Medicago arborea and M. strasseri (Fabaceae).<h4>Background</h4>Whole genome duplication plays a central role in plant evolution. There are two main classes of polyploid formation: autopolyploids which arise within one species by doubling of similar homologous genomes; in contrast, allopolyploidy (hybrid polyploidy) arise via hybridization and subsequent doubling of nonhomologous (homoeologous) genomes. The distinction between polyploid origins can be made using gene phylogenies, if alleles from each genome can be correctly retrieved. We examined whether two closely related tetraploid Mediterranean shrubs (Medicago arborea and M. strasseri) have an allopolyploid origin - a question that has remained unsolved despite substantial previous research. We sequenced and analyzed ten low-copy nuclear genes from these and related species, pha2018-01-01T00:00:00Z2018 Jan2025-04-04T12:31:30.249Z2019-03-26T23:00:49ZS-EPMC57872882937446110.1186/s12862-018-1127-z