biostudies-literatureBare MInstituto de Salud Carlos IIIIstituto de Salud Carlos IIIKRONIKGUNE –Centro de Investigación en CronicidadThe Department of Health of the Basque CountryKRONIKGUNE -Centro de Investigación en CronicidadEuropean Regional Development Fund49https://www.ebi.ac.uk/biostudies/studies/S-EPMC5789585biostudies-literatureUnknown18(1)<h4>Background</h4>To validate and recalibrate the CR- POSSUM model and compared its discriminatory capacity with other European models such as POSSUM, P-POSSUM, AFC or IRCS to predict operative mortality in surgery for colorectal cancer.<h4>Methods</h4>Prospective multicenter cohort study from 22 hospitals in Spain. We included patients undergoing planned or urgent surgery for primary invasive colorectal cancers between June 2010 and December 2012 (N = 2749). Clinical data were gathered through medical chart review. We validated and recalibrated the predictive models using logistic regression techniques. To calculate the discriminatory power of each model, we estimated the areas under the curve - AUC (95% CI). We also assessed the calibration of the models by applying the Hosmer-Lemeshow BMC health services researchValidity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality.PMC57895852010111098KRONIK 11/006thematic networks - REDISSEC (Health Services Research on Chronic Diseases Network (RD12/0001/0007)PS09/00805, PI09/90441, PS09/00314, PS09/00910, PS09/00746, PI09/90460, PI09/90490, PI09/90397, PI09/90453Loizate AEspinas JAGonzalez NMayol JABlasco JACantero RTora NCormenzana EMartin JComas MArostegui IAlmazan CUrkidi IDujovne PEspallargues MGuadalajara HCARESS-CCR Study GroupQuintana JMGarcia SBilbao ASotelo AIGarcia DEnriquez JMDel Cura IPont MDel Rey AMorales MMCollera PAnton ASarasqueta CMorey MRivas FRedondo MPerales ABare MErro JMErrasti JHeras MAguirre UFernandez NAnula RAlcantara MJEscobar AFernandez JMPlacer CGimeno AZBriones ECampano ELafuente IOrive MGil MJMedina FGomez SPera MLazaro SfalseValidity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality.<h4>Background</h4>To validate and recalibrate the CR- POSSUM model and compared its discriminatory capacity with other European models such as POSSUM, P-POSSUM, AFC or IRCS to predict operative mortality in surgery for colorectal cancer.<h4>Methods</h4>Prospective multicenter cohort study from 22 hospitals in Spain. We included patients undergoing planned or urgent surgery for primary invasive colorectal cancers between June 2010 and December 2012 (N = 2749). Clinical data were gathered through medical chart review. We validated and recalibrated the predictive models using logistic regression techniques. To calculate the discriminatory power of each model, we estimated the areas under the curve - AUC (95% CI). We also assessed the calibration of the models by applying the Hosmer-Lemeshow 2018-01-01T00:00:00Z2018 Jan2026-06-07T03:13:24.175Z2019-03-26T23:01:06ZS-EPMC57895852937864710.1186/s12913-018-2839-x