{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["4"],"submitter":["Dashtiyan AA"],"pubmed_abstract":["The aim of this study was to investigate the effect of endurance training with and without vitamin E on the expression of p53 and Phosphatase and tension homolog (PTEN) tumor suppressor genes of prostate glands in male rats. For this purpose, 50 Sprague-Dawley male rats were randomly assigned into 5 groups: (1) control group (CON, n = 10), (2) sham (S, n = 10), (3) endurance training (ET, n = 10), (4) endurance training + vitamin E (ET + VE, n = 10), (5) vitamin E (VE, n = 10). Endurance training protocol was implemented for 6 weeks, 6 days per week, in accordance with the overload principle. To measure expression changes of p53 and PTEN genes in rats' prostate, real-time PCR method was used and HPLC method was used to measure vitamin E in this tissue. After 6 weeks of taking vitamin E, it"],"journal":["Biochimie open"],"pagination":["112-118"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5801830"],"repository":["biostudies-literature"],"pubmed_title":["The effect of endurance training with and without vitamin E on expression of p53 and PTEN tumor suppressing genes in prostate glands of male rats."],"pmcid":["PMC5801830"],"pubmed_authors":["Sepehrimanesh M","Dashtiyan AA","Tanideh N","Afzalpour ME"],"additional_accession":[]},"is_claimable":false,"name":"The effect of endurance training with and without vitamin E on expression of p53 and PTEN tumor suppressing genes in prostate glands of male rats.","description":"The aim of this study was to investigate the effect of endurance training with and without vitamin E on the expression of p53 and Phosphatase and tension homolog (PTEN) tumor suppressor genes of prostate glands in male rats. For this purpose, 50 Sprague-Dawley male rats were randomly assigned into 5 groups: (1) control group (CON, n = 10), (2) sham (S, n = 10), (3) endurance training (ET, n = 10), (4) endurance training + vitamin E (ET + VE, n = 10), (5) vitamin E (VE, n = 10). Endurance training protocol was implemented for 6 weeks, 6 days per week, in accordance with the overload principle. To measure expression changes of p53 and PTEN genes in rats' prostate, real-time PCR method was used and HPLC method was used to measure vitamin E in this tissue. After 6 weeks of taking vitamin E, it","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jun","modification":"2025-04-21T20:36:50.678Z","creation":"2019-03-26T23:03:07Z"},"accession":"S-EPMC5801830","cross_references":{"pubmed":["29450148"],"doi":["10.1016/j.biopen.2017.03.005"]}}