biostudies-literatureUnknown46(6)Bouvier AMNational Cancer Institute<h4>Background</h4>Pancreatic cancer is one of the most lethal. Most countries have exhibited a stable or decreasing incidence over time. The aim of this study was to provide updated French temporal trends in pancreatic cancer incidence and mortality over the past three decades.<h4>Methods</h4>Incidence was estimated using the French National Network of Cancer Registries (FRANCIM) and mortality using the French Mortality Statistics Office. World age-standardized incidence and mortality were modelled by age-period-cohort models. The net cumulative risk of developing pancreatic cancer by birth cohort was calculated, as were annual percentage changes (APCs) in incidence and mortality.<h4>Results</h4>Between 1982 and 2012, age-standardized incidence increased from 4.8 in 1980 to 9.6 per 100 00International journal of epidemiology1764-1772https://www.ebi.ac.uk/biostudies/studies/S-EPMC5837593biostudies-literatureFocus on an unusual rise in pancreatic cancer incidence in France.PMC5837593Bouvier AMLaunoy GFrench Network of Cancer Registries (FRANCIM)Drouillard ARemontet LLeone NUhry ZJooste VfalseFocus on an unusual rise in pancreatic cancer incidence in France.<h4>Background</h4>Pancreatic cancer is one of the most lethal. Most countries have exhibited a stable or decreasing incidence over time. The aim of this study was to provide updated French temporal trends in pancreatic cancer incidence and mortality over the past three decades.<h4>Methods</h4>Incidence was estimated using the French National Network of Cancer Registries (FRANCIM) and mortality using the French Mortality Statistics Office. World age-standardized incidence and mortality were modelled by age-period-cohort models. The net cumulative risk of developing pancreatic cancer by birth cohort was calculated, as were annual percentage changes (APCs) in incidence and mortality.<h4>Results</h4>Between 1982 and 2012, age-standardized incidence increased from 4.8 in 1980 to 9.6 per 100 002017-01-01T00:00:00Z2017 Dec2026-06-18T03:45:12.574Z2019-03-27T00:09:27ZS-EPMC58375932860550010.1093/ije/dyx088