biostudies-literatureUnknown38(42)Escaned JNational Institutes of Health<h4>Aims</h4>To investigate if recent technical and procedural developments in percutaneous coronary intervention (PCI) significantly influence outcomes in appropriately selected patients with three-vessel (3VD) coronary artery disease.<h4>Methods and results</h4>The SYNTAX II study is a multicenter, all-comers, open-label, single arm study that investigated the impact of a contemporary PCI strategy on clinical outcomes in patients with 3VD in 22 centres from four European countries. The SYNTAX-II strategy includes: heart team decision-making utilizing the SYNTAX Score II (a clinical tool combining anatomical and clinical factors), coronary physiology guided revascularisation, implantation of thin strut bioresorbable-polymer drug-eluting stents, intravascular ultrasound (IVUS) guided stentEuropean heart journal3124-3134https://www.ebi.ac.uk/biostudies/studies/S-EPMC5837643biostudies-literatureClinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study.PMC5837643Ochala AHanratty CRyan NOnuma YEj West NStables RHvan Es GAFath-Ordoubadi FSerruys PWCruz-Gonzalez ISabate MHildick-Smith DHoole SPAppleby CUren NZueco JTaggart DPFarooq VPiek JJIniguez Avan Geuns RJWalsh SDudek DLesiak MBuszman PKappetein APMorel MAEscaned JZaman ACavalcante RCollet CMoreno RDe Maria GLDavies Jvan Mieghem NBanning APde Vries TGoicolea JfalseClinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study.<h4>Aims</h4>To investigate if recent technical and procedural developments in percutaneous coronary intervention (PCI) significantly influence outcomes in appropriately selected patients with three-vessel (3VD) coronary artery disease.<h4>Methods and results</h4>The SYNTAX II study is a multicenter, all-comers, open-label, single arm study that investigated the impact of a contemporary PCI strategy on clinical outcomes in patients with 3VD in 22 centres from four European countries. The SYNTAX-II strategy includes: heart team decision-making utilizing the SYNTAX Score II (a clinical tool combining anatomical and clinical factors), coronary physiology guided revascularisation, implantation of thin strut bioresorbable-polymer drug-eluting stents, intravascular ultrasound (IVUS) guided stent2017-01-01T00:00:00Z2017 Nov2026-05-05T23:14:07.713Z2019-03-26T23:06:54ZS-EPMC58376432902036710.1093/eurheartj/ehx512