biostudies-literatureMay MNCI NIH HHS72-85https://www.ebi.ac.uk/biostudies/studies/S-EPMC5843540biostudies-literatureUnknown16(1)PURPOSE OF REVIEW:Analysis of the esophageal microbiome remains a relatively new field of research, and most studies to date have focused on characterizing the esophageal microbiome in states of health and disease. Microbiome alterations have been implicated in the pathogenesis of inflammatory and neoplastic conditions in the colon and elsewhere in the gastrointestinal tract. The epidemiology of various esophageal conditions including Barrett's esophagus (BE), esophageal adenocarcinoma (EAC), esophageal squamous cell carcinoma (ESCC), and eosinophilic esophagitis (EoE) point to the microbiome as a potential co-factor in disease pathogenesis, and the possibility exists that these microbiome alterations could contribute directly to the inflammatory environments necessary for the carcinogenesCurrent treatment options in gastroenterologyEmerging Insights into the Esophageal Microbiome.PMC5843540U54 CA163004Abrams JAMay MfalseEmerging Insights into the Esophageal Microbiome.PURPOSE OF REVIEW:Analysis of the esophageal microbiome remains a relatively new field of research, and most studies to date have focused on characterizing the esophageal microbiome in states of health and disease. Microbiome alterations have been implicated in the pathogenesis of inflammatory and neoplastic conditions in the colon and elsewhere in the gastrointestinal tract. The epidemiology of various esophageal conditions including Barrett's esophagus (BE), esophageal adenocarcinoma (EAC), esophageal squamous cell carcinoma (ESCC), and eosinophilic esophagitis (EoE) point to the microbiome as a potential co-factor in disease pathogenesis, and the possibility exists that these microbiome alterations could contribute directly to the inflammatory environments necessary for the carcinogenes2018-01-01T00:00:00Z2018 Mar2025-04-05T16:02:41.028Z2019-06-06T19:06:00ZS-EPMC58435402935033910.1007/s11938-018-0171-5