{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Kimura S"],"pubmed_abstract":["The freshwater cyanobacterium <i>Microcystis aeruginosa</i> frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. Here, to assess <i>Microcystis</i> population dynamics associated with exogenous mobile genetic elements such as phages and plasmids, we examined the temporal variation in CRISPR genotypes (CTs) by analyzing spacer sequences detected in a natural pond between June and October 2013 when a cyanobacterial bloom occurred. A total of 463,954 high-quality leader-end CRISPR sequences were obtained and the sequen"],"journal":["Frontiers in microbiology"],"pagination":["425"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5852275"],"repository":["biostudies-literature"],"pubmed_title":["Incomplete Selective Sweeps of <i>Microcystis</i> Population Detected by the Leader-End CRISPR Fragment Analysis in a Natural Pond."],"pmcid":["PMC5852275"],"pubmed_authors":["Morimoto D","Sako Y","Yamanaka M","Kimura S","Yoshida T","Uehara M"],"additional_accession":[]},"is_claimable":false,"name":"Incomplete Selective Sweeps of <i>Microcystis</i> Population Detected by the Leader-End CRISPR Fragment Analysis in a Natural Pond.","description":"The freshwater cyanobacterium <i>Microcystis aeruginosa</i> frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. Here, to assess <i>Microcystis</i> population dynamics associated with exogenous mobile genetic elements such as phages and plasmids, we examined the temporal variation in CRISPR genotypes (CTs) by analyzing spacer sequences detected in a natural pond between June and October 2013 when a cyanobacterial bloom occurred. A total of 463,954 high-quality leader-end CRISPR sequences were obtained and the sequen","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-04-08T00:05:43.477Z","creation":"2019-03-26T23:23:01Z"},"accession":"S-EPMC5852275","cross_references":{"pubmed":["29568293"],"doi":["10.3389/fmicb.2018.00425"]}}