{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(3)"],"submitter":["Peters SAE"],"pubmed_abstract":["<h4>Objective</h4>To assess the relationship between risk factor clusters and cardiovascular disease (CVD) incidence in Asian and Caucasian populations and to estimate the burden of CVD attributable to each cluster.<h4>Setting</h4>Asia Pacific Cohort Studies Collaboration.<h4>Participants</h4>Individual participant data from 34 population-based cohorts, involving 314 024 participants without a history of CVD at baseline.<h4>Outcome measures</h4>Clusters were 11 possible combinations of four individual risk factors (current smoking, overweight, blood pressure (BP) and total cholesterol). Cox regression models were used to obtain adjusted HRs and 95% CIs for CVD associated with individual risk factors and risk factor clusters. Population-attributable fractions (PAFs) were calculated.<h4>Resu"],"journal":["BMJ open"],"pagination":["e019335"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5855160"],"repository":["biostudies-literature"],"pubmed_title":["Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration."],"pmcid":["PMC5855160"],"pubmed_authors":["Luszcz M","Liu LS","Kagaya M","Macmahon S","Suh I","Hirakawa Y","Knuiman MW","Zhou BF","Chen LQ","Tamakoshi A","Zhang HY","Okayama H","Jamrozik K","Nakachi K","Hata J","Imai Y","Wang X","Hozawa A","Kita Y","Hughes K","Woo J","Tang Z","Peters SAE","Tanaka H","Lam TH","Heng D","Li YH","Ueshima H","Wu XG","Asia Pacific Cohort Studies Collaboration","Ninomiya T","Huxley R","Maegawa H","Sritara P","He Y","Yao CH","Yao SX","Ho S","Norton R","Broadhurst R","Christensen H","Matsutani Y","Ho SC","Shan GL","Huang MS","Lee J","Gu DF","Shimamoto K","Kim IS","Bots ML","Yu XH","Jee SH","R Choudhury S","Hashimoto T","Zhou B","Pan WH","Giles GG","Xie JX","Jiang CQ","Norman P","Ohkubo T","Chen ZM","Chew SK","Welborn TA","Zhou J","Vaartjes I","Nozaki A","Rodgers A","Aoki N","Wu ZS","Hobbs M","Saitoh S","Woodward M","Jackson R","Whitlock G","Duan XF","Ameratunga S","Wu ZL","H Pan W","Li SC","Horibe H","Knuiman M","Fang X","Hong Z","Imai ADY","Kim HC","Fuh JL","Yang QD","Li ZZ","Sakata K","H Fang X"],"additional_accession":[]},"is_claimable":false,"name":"Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration.","description":"<h4>Objective</h4>To assess the relationship between risk factor clusters and cardiovascular disease (CVD) incidence in Asian and Caucasian populations and to estimate the burden of CVD attributable to each cluster.<h4>Setting</h4>Asia Pacific Cohort Studies Collaboration.<h4>Participants</h4>Individual participant data from 34 population-based cohorts, involving 314 024 participants without a history of CVD at baseline.<h4>Outcome measures</h4>Clusters were 11 possible combinations of four individual risk factors (current smoking, overweight, blood pressure (BP) and total cholesterol). Cox regression models were used to obtain adjusted HRs and 95% CIs for CVD associated with individual risk factors and risk factor clusters. Population-attributable fractions (PAFs) were calculated.<h4>Resu","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2025-04-04T09:06:17.311Z","creation":"2019-03-26T22:47:16Z"},"accession":"S-EPMC5855160","cross_references":{"pubmed":["29511013"],"doi":["10.1136/bmjopen-2017-019335"]}}