biostudies-literatureUnknown3(1)Parekh A<h4>Purpose</h4>The associations among radiation fractionation, body mass index (BMI), and acute skin toxicity with adjuvant radiation for breast cancer is of increasing interest. This study evaluated the rate of grade ≥2 dermatitis and moist desquamation (MD) in patients with a high BMI who were treated to the breast or chest wall to understand the role of radiation target, fractionation regimen, and BMI.<h4>Methods and materials</h4>We retrospectively evaluated 280 patients treated with adjuvant radiation for breast cancer after up-front surgery. We collected information on patient demographics, disease and treatment characteristics, and acute skin toxicities. Multiple logistic regression models were used to evaluate for predictors of grade ≥2 dermatitis and MD.<h4>Results</h4>Patients uAdvances in radiation oncology8-15https://www.ebi.ac.uk/biostudies/studies/S-EPMC5856985biostudies-literaturePredictors of radiation-induced acute skin toxicity in breast cancer at a single institution: Role of fractionation and treatment volume.PMC5856985Camp MAsrari FHabibi MParekh ADholakia ADZellars RWright JLZabranksy DJfalsePredictors of radiation-induced acute skin toxicity in breast cancer at a single institution: Role of fractionation and treatment volume.<h4>Purpose</h4>The associations among radiation fractionation, body mass index (BMI), and acute skin toxicity with adjuvant radiation for breast cancer is of increasing interest. This study evaluated the rate of grade ≥2 dermatitis and moist desquamation (MD) in patients with a high BMI who were treated to the breast or chest wall to understand the role of radiation target, fractionation regimen, and BMI.<h4>Methods and materials</h4>We retrospectively evaluated 280 patients treated with adjuvant radiation for breast cancer after up-front surgery. We collected information on patient demographics, disease and treatment characteristics, and acute skin toxicities. Multiple logistic regression models were used to evaluate for predictors of grade ≥2 dermatitis and MD.<h4>Results</h4>Patients u2018-01-01T00:00:00Z2018 Jan-Mar2025-04-21T22:54:57.506Z2019-06-06T19:09:07ZS-EPMC58569852955657310.1016/j.adro.2017.10.007