{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Park Y"],"funding":["NICHD NIH HHS","NIA NIH HHS","NIMH NIH HHS"],"pagination":["k1218"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5871903"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["360"],"pubmed_abstract":["<h4>Objective</h4>To compare the risk of in-hospital mortality associated with haloperidol compared with atypical antipsychotics in patients admitted to hospital with acute myocardial infarction.<h4>Design</h4>Cohort study using a healthcare database.<h4>Setting</h4>Nationwide sample of patient data from more than 700 hospitals across the United States.<h4>Participants</h4>6578 medical patients aged more than 18 years who initiated oral haloperidol or oral atypical antipsychotics (olanzapine, quetiapine, risperidone) during a hospital admission with a primary diagnosis of acute myocardial infarction between 2003 and 2014.<h4>Main outcome measure</h4>In-hospital mortality during seven days of follow-up from treatment initiation.<h4>Results</h4>Among 6578 patients (mean age 75.2 years) treat"],"journal":["BMJ (Clinical research ed.)"],"pubmed_title":["Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: cohort study."],"pmcid":["PMC5871903"],"funding_grant_id":["K08 HD075831","K01 MH099141","K08 AG051187"],"pubmed_authors":["Kim DH","Park Y","Huybrechts KF","Patorno E","Hernandez-Diaz S","Mogun H","Glynn RJ","Bateman BT"],"additional_accession":[]},"is_claimable":false,"name":"Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: cohort study.","description":"<h4>Objective</h4>To compare the risk of in-hospital mortality associated with haloperidol compared with atypical antipsychotics in patients admitted to hospital with acute myocardial infarction.<h4>Design</h4>Cohort study using a healthcare database.<h4>Setting</h4>Nationwide sample of patient data from more than 700 hospitals across the United States.<h4>Participants</h4>6578 medical patients aged more than 18 years who initiated oral haloperidol or oral atypical antipsychotics (olanzapine, quetiapine, risperidone) during a hospital admission with a primary diagnosis of acute myocardial infarction between 2003 and 2014.<h4>Main outcome measure</h4>In-hospital mortality during seven days of follow-up from treatment initiation.<h4>Results</h4>Among 6578 patients (mean age 75.2 years) treat","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2025-04-26T06:50:32.243Z","creation":"2019-03-26T23:20:55Z"},"accession":"S-EPMC5871903","cross_references":{"pubmed":["29592958"],"doi":["10.1136/bmj.k1218"]}}