biostudies-literatureRiley EANational Institute of Environmental Health SciencesNIEHS NIH HHSNIOSH CDC HHSNational Institute of Occupational Safety and Health339-350https://www.ebi.ac.uk/biostudies/studies/S-EPMC5873526biostudies-literatureUnknown62(3)We investigated the viability of particle bound 1-nitropyrene (1-NP) air concentration measurements as a surrogate of diesel exhaust (DE) exposure, as compared with industry-standard elemental carbon (EC) and total carbon (TC) measurements. Personal exposures are reported for 18 employees at a large underground metal mine during four different monitoring campaigns. Full-shift personal air exposure sampling was conducted using a Mine Safety and Health Administration (MSHA) compliant diesel particulate matter (DPM) impactor cassette downstream of a GS-1 cyclone pre-selector. Each DPM filter element was analyzed for EC and organic carbon (OC) using NIOSH Method 5040. After EC and OC analysis, the remaining portion of each DPM filter was analyzed for 1-NP using liquid chromatography tandem masAnnals of work exposures and healthEvaluation of 1-Nitropyrene as a Surrogate Measure for Diesel Exhaust.PMC5873526T32 ES015459R21 OH010362P30 ES007033T42 OH008433P30ES007033Carpenter EEZamzow ESpear TMRiley EASeixas NSSheppard LRamsay JPyke CStephenson DJPaulsen MHSimpson CDfalseEvaluation of 1-Nitropyrene as a Surrogate Measure for Diesel Exhaust.We investigated the viability of particle bound 1-nitropyrene (1-NP) air concentration measurements as a surrogate of diesel exhaust (DE) exposure, as compared with industry-standard elemental carbon (EC) and total carbon (TC) measurements. Personal exposures are reported for 18 employees at a large underground metal mine during four different monitoring campaigns. Full-shift personal air exposure sampling was conducted using a Mine Safety and Health Administration (MSHA) compliant diesel particulate matter (DPM) impactor cassette downstream of a GS-1 cyclone pre-selector. Each DPM filter element was analyzed for EC and organic carbon (OC) using NIOSH Method 5040. After EC and OC analysis, the remaining portion of each DPM filter was analyzed for 1-NP using liquid chromatography tandem mas2018-01-01T00:00:00Z2018 Mar2025-04-26T03:34:22.973Z2019-08-04T07:25:49ZS-EPMC58735262930080910.1093/annweh/wxx111