biostudies-literatureXu WNational Natural Science Foundation of China3201203https://www.ebi.ac.uk/biostudies/studies/S-EPMC5885346biostudies-literatureUnknown2018Carbamazepine is known to produce the side effect of euphoria. As such, it lends itself to being a drug of abuse, particularly in the adolescent population. This retrospective study evaluated carbamazepine abuse, treatment course, and associated morbidity in Chinese adolescents. The median dose of carbamazepine resulting in overdose was 2,000 mg (800-5,000). Patients were largely from urban-rural fringe areas (76.47%, 52.94%) with school performance within the last 1/3 range and (52.94%) unsupervised by parents. 35.29% experienced an obvious sense of euphoria. All patients had nervous system symptoms, 6 (35.29%) cases developed coma (GCS < 8), and 5 (29.41%) cases experienced convulsion. Four cases were treated with hemodialysis. The incidence rate in young patients with repeat carbamazepiBioMed research internationalA Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents.PMC588534620170541023817716218137203981270726Liu CFWang LJLi JJXu WChen YLZhao YfalseA Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents.Carbamazepine is known to produce the side effect of euphoria. As such, it lends itself to being a drug of abuse, particularly in the adolescent population. This retrospective study evaluated carbamazepine abuse, treatment course, and associated morbidity in Chinese adolescents. The median dose of carbamazepine resulting in overdose was 2,000 mg (800-5,000). Patients were largely from urban-rural fringe areas (76.47%, 52.94%) with school performance within the last 1/3 range and (52.94%) unsupervised by parents. 35.29% experienced an obvious sense of euphoria. All patients had nervous system symptoms, 6 (35.29%) cases developed coma (GCS < 8), and 5 (29.41%) cases experienced convulsion. Four cases were treated with hemodialysis. The incidence rate in young patients with repeat carbamazepi2018-01-01T00:00:00Z20182025-04-21T19:54:40.359Z2019-03-26T23:37:34ZS-EPMC58853462976598310.1155/2018/3201203