biostudies-literatureUnknown29(8)Kama RCdc48/p97 and the ubiquilin family of UBA-UBL proteins are known for their role in the retrotranslocation of damaged proteins from the endoplasmic reticulum. We demonstrate that Cdc48 and the ubiquilin-like proteins in yeast also play a role in the anterograde trafficking of proteins, in this case the vacuolar protease, Cps1.Molecular biology of the cell948-963https://www.ebi.ac.uk/biostudies/studies/S-EPMC5896933biostudies-literatureCdc48 and ubiquilins confer selective anterograde protein sorting and entry into the multivesicular body in yeast.PMC5896933Kama RKanneganti VGerst JEGabriely GfalseCdc48 and ubiquilins confer selective anterograde protein sorting and entry into the multivesicular body in yeast.Cdc48/p97 and the ubiquilin family of UBA-UBL proteins are known for their role in the retrotranslocation of damaged proteins from the endoplasmic reticulum. We demonstrate that Cdc48 and the ubiquilin-like proteins in yeast also play a role in the anterograde trafficking of proteins, in this case the vacuolar protease, Cps1.2018-01-01T00:00:00Z2018 Apr2026-07-16T11:26:49.506Z2019-03-26T23:43:23ZS-EPMC58969332944495810.1091/mbc.E17-11-0652