biostudies-literatureUnknown20(93)Marchiori LLM<h4>Context</h4>Tinnitus is a common disorder that occurs frequently across all strata of population and has an important health concern and is often associated with different forms of the hearing loss of varying severity.<h4>Aims</h4>To investigate the association between the polymorphism of tumor necrosis factor alpha (TNFα) in the region -308 G/A with the susceptibility to tinnitus in individuals with the history of exposure to occupational noise.<h4>Settings and design</h4>This was a cross-sectional study with a sample of 179 independent elderly people above 60 years of age.<h4>Materials and methods</h4>Information on exposure to occupational noise was obtained by interviews. Audiological evaluation was performed using pure tone audiometry and genotyped through polymerase chain reactioNoise & health37-41https://www.ebi.ac.uk/biostudies/studies/S-EPMC5926314biostudies-literatureAssociation between polymorphism of tumor necrosis factor alpha (tnfα) in the region -308 g/a with tinnitus in the elderly with a history of occupational noise exposure.PMC5926314Poly-Frederico RCGoncalvez ASDias ACMDoi MYMarchiori LLMfalseAssociation between polymorphism of tumor necrosis factor alpha (tnfα) in the region -308 g/a with tinnitus in the elderly with a history of occupational noise exposure.<h4>Context</h4>Tinnitus is a common disorder that occurs frequently across all strata of population and has an important health concern and is often associated with different forms of the hearing loss of varying severity.<h4>Aims</h4>To investigate the association between the polymorphism of tumor necrosis factor alpha (TNFα) in the region -308 G/A with the susceptibility to tinnitus in individuals with the history of exposure to occupational noise.<h4>Settings and design</h4>This was a cross-sectional study with a sample of 179 independent elderly people above 60 years of age.<h4>Materials and methods</h4>Information on exposure to occupational noise was obtained by interviews. Audiological evaluation was performed using pure tone audiometry and genotyped through polymerase chain reactio2018-01-01T00:00:00Z2018 Mar-Apr2025-04-25T18:27:05.985Z2019-03-26T23:34:37ZS-EPMC59263142967629310.4103/nah.NAH_34_17