{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stites SD"],"funding":["NIA NIH HHS","National Institute on Aging"],"pagination":["974-985"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5927082"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["72(6)"],"pubmed_abstract":["<h4>Objective</h4>This study examined how awareness of diagnostic label impacted self-reported quality of life (QOL) in persons with varying degrees of cognitive impairment.<h4>Method</h4>Older adults (n = 259) with normal cognition, Mild Cognitive Impairment (MCI), or mild Alzheimer's disease dementia (AD) completed tests of cognition and self-report questionnaires that assessed diagnosis awareness and multiple domains of QOL: cognitive problems, activities of daily living, physical functioning, mental wellbeing, and perceptions of one's daily life. We compared measures of QOL by cognitive performance, diagnosis awareness, and diagnostic group.<h4>Results</h4>Persons with MCI or AD who were aware of their diagnosis reported lower average satisfaction with daily life (QOL-AD), basic functioning (BADL Scale), and physical wellbeing (SF-12 PCS), and more difficulties in daily life (DEM-QOL) than those who were unaware (all p ≤ .007). Controlling for gender, those expecting their condition to worsen over time reported greater depression (GDS), higher stress (PSS), lower quality of daily life (QOL-AD, DEM-QOL), and more cognitive difficulties (CDS) compared to others (all p < .05).<h4>Discussion</h4>Persons aware of their diagnostic label-either MCI or AD-and its prognosis report lower QOL than those unaware of these facts about themselves. These relationships are independent of the severity of cognitive impairment."],"journal":["The journals of gerontology. Series B, Psychological sciences and social sciences"],"pubmed_title":["Awareness of Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia Diagnoses Associated With Lower Self-Ratings of Quality of Life in Older Adults."],"pmcid":["PMC5927082"],"funding_grant_id":["P30 AG010124","P30-AG-010124"],"pubmed_authors":["Karlawish J","Rubright JD","Stites SD","Harkins K","Wolk D"],"additional_accession":[]},"is_claimable":false,"name":"Awareness of Mild Cognitive Impairment and Mild Alzheimer's Disease Dementia Diagnoses Associated With Lower Self-Ratings of Quality of Life in Older Adults.","description":"<h4>Objective</h4>This study examined how awareness of diagnostic label impacted self-reported quality of life (QOL) in persons with varying degrees of cognitive impairment.<h4>Method</h4>Older adults (n = 259) with normal cognition, Mild Cognitive Impairment (MCI), or mild Alzheimer's disease dementia (AD) completed tests of cognition and self-report questionnaires that assessed diagnosis awareness and multiple domains of QOL: cognitive problems, activities of daily living, physical functioning, mental wellbeing, and perceptions of one's daily life. We compared measures of QOL by cognitive performance, diagnosis awareness, and diagnostic group.<h4>Results</h4>Persons with MCI or AD who were aware of their diagnosis reported lower average satisfaction with daily life (QOL-AD), basic functioning (BADL Scale), and physical wellbeing (SF-12 PCS), and more difficulties in daily life (DEM-QOL) than those who were unaware (all p ≤ .007). Controlling for gender, those expecting their condition to worsen over time reported greater depression (GDS), higher stress (PSS), lower quality of daily life (QOL-AD, DEM-QOL), and more cognitive difficulties (CDS) compared to others (all p < .05).<h4>Discussion</h4>Persons aware of their diagnostic label-either MCI or AD-and its prognosis report lower QOL than those unaware of these facts about themselves. These relationships are independent of the severity of cognitive impairment.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Oct","modification":"2025-04-04T09:24:29.774Z","creation":"2019-03-26T23:58:10Z"},"accession":"S-EPMC5927082","cross_references":{"pubmed":["28958089"],"doi":["10.1093/geronb/gbx100"]}}