biostudies-literatureUnknown6(5)Coton JChromosomal microarray (CMA) can detect pathogenic copy number variations in 15-20% of individuals with intellectual disability and in 10% of patients with autism spectrum disorders. The diagnostic rate in specific learning disorders (SLD) is unknown. Our study emphasizes the usefulness of CMA in the diagnostic workout assessment of familial SLD.Clinical case reports827-834https://www.ebi.ac.uk/biostudies/studies/S-EPMC5930267biostudies-literatureCharacterization of two familial cases presenting with a syndromic specific learning disorder and carrying (17q;21q) unbalanced translocations.PMC5930267Labalme ABussy GSanlaville DCoton JTill Mdes Portes VLesca GEdery PRossi MHeron DKrifi Papoz SfalseCharacterization of two familial cases presenting with a syndromic specific learning disorder and carrying (17q;21q) unbalanced translocations.Chromosomal microarray (CMA) can detect pathogenic copy number variations in 15-20% of individuals with intellectual disability and in 10% of patients with autism spectrum disorders. The diagnostic rate in specific learning disorders (SLD) is unknown. Our study emphasizes the usefulness of CMA in the diagnostic workout assessment of familial SLD.2018-01-01T00:00:00Z2018 May2024-11-20T18:13:07.567Z2019-03-26T23:37:01ZS-EPMC59302672974406610.1002/ccr3.1450