{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen YL"],"funding":["Guangdong Medical Scientific Research Foundation","Natural Science Foundation of Guangdong Province","National Natural Science Foundation of China","Key Program of Young Teachers Foundation of Sun Yat-sen University"],"pagination":["81"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5932798"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>Previous studies have revealed that hepatitis B virus (HBV) infection may be associated with rheumatoid arthritis (RA), while there are no further clinical studies regarding the role of HBV infection in RA progression during disease-modifying anti-rheumatic drug (DMARD) therapy. Here, we aimed to explore the influence of HBV infection on radiographic and clinical outcomes among patients with RA in a clinical practice setting.<h4>Methods</h4>Thirty-two consecutive patients with RA (Disease Activity Score 28-joint assessment based on C-reactive protein (DAS28-CRP) ≥2.6) with chronic HBV infection (CHB) were retrospectively recruited as the CHB group and 128 age-matched, sex-matched, and disease activity-matched contemporary patients with RA without CHB were included in the"],"journal":["Arthritis research & therapy"],"pubmed_title":["Deleterious role of hepatitis B virus infection in therapeutic response among patients with rheumatoid arthritis in a clinical practice setting: a case-control study."],"pmcid":["PMC5932798"],"funding_grant_id":["2016A030313307","17ykjc12","81471597","81671612","2017A030313576","A2017109","81601427","2014A030313074"],"pubmed_authors":["Yang ZH","Dai L","Lin JZ","Li QH","Mo YQ","Yan T","Zheng DH","Chen YL","Ma JD","Wang XY"],"additional_accession":[]},"is_claimable":false,"name":"Deleterious role of hepatitis B virus infection in therapeutic response among patients with rheumatoid arthritis in a clinical practice setting: a case-control study.","description":"<h4>Background</h4>Previous studies have revealed that hepatitis B virus (HBV) infection may be associated with rheumatoid arthritis (RA), while there are no further clinical studies regarding the role of HBV infection in RA progression during disease-modifying anti-rheumatic drug (DMARD) therapy. Here, we aimed to explore the influence of HBV infection on radiographic and clinical outcomes among patients with RA in a clinical practice setting.<h4>Methods</h4>Thirty-two consecutive patients with RA (Disease Activity Score 28-joint assessment based on C-reactive protein (DAS28-CRP) ≥2.6) with chronic HBV infection (CHB) were retrospectively recruited as the CHB group and 128 age-matched, sex-matched, and disease activity-matched contemporary patients with RA without CHB were included in the","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 May","modification":"2025-05-29T21:21:42.003Z","creation":"2025-05-29T21:21:42.003Z"},"accession":"S-EPMC5932798","cross_references":{"pubmed":["29720221"],"doi":["10.1186/s13075-018-1548-5"]}}