{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang MJ"],"funding":["the Key Technology R&amp;D Program"],"pagination":["234"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5964880"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(1)"],"pubmed_abstract":["<h4>Background</h4>With the widespread use of rifampicin and isoniazid, bacterial resistance has become a growing problem. Additionally, the lack of relevant baseline information for the frequency of drug-resistant tuberculosis (TB) gene mutations is a critical issue, and the incidence of this infection in the city of Changchun has not investigated to date. However, compared with the slow traditional methods of drug susceptibility testing, recently developed detection methods, such as rifampicin and isoniazid resistance-related gene chip techniques, allow for rapid, easy detection and simultaneous testing for mutation frequency and drug resistance.<h4>Methods</h4>In this study, the rifampicin and isoniazid resistance-related gene mutation chip method was employed for an epidemiological inv"],"journal":["BMC infectious diseases"],"pubmed_title":["GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun."],"pmcid":["PMC5964880"],"funding_grant_id":["20170623032TC","2015BAI07B02"],"pubmed_authors":["Liu Y","Sun XJ","Zhang MJ","Yuan B","Ren WZ","Liu KW","Gao W","Ji ZH"],"additional_accession":[]},"is_claimable":false,"name":"GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun.","description":"<h4>Background</h4>With the widespread use of rifampicin and isoniazid, bacterial resistance has become a growing problem. Additionally, the lack of relevant baseline information for the frequency of drug-resistant tuberculosis (TB) gene mutations is a critical issue, and the incidence of this infection in the city of Changchun has not investigated to date. However, compared with the slow traditional methods of drug susceptibility testing, recently developed detection methods, such as rifampicin and isoniazid resistance-related gene chip techniques, allow for rapid, easy detection and simultaneous testing for mutation frequency and drug resistance.<h4>Methods</h4>In this study, the rifampicin and isoniazid resistance-related gene mutation chip method was employed for an epidemiological inv","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 May","modification":"2025-04-05T10:58:31.643Z","creation":"2019-03-26T23:38:34Z"},"accession":"S-EPMC5964880","cross_references":{"pubmed":["29788948"],"doi":["10.1186/s12879-018-3131-8"]}}