biostudies-literatureUnknown18(1)Ssonko M<h4>Background</h4>Polypharmacy has not been investigated in patients living with HIV in developing countries. The aims of this study were to determine the prevalence of polypharmacy, the factors associated with polypharmacy and whether polypharmacy was associated with adverse effects among older adults on anti-retroviral therapy (ART).<h4>Methods</h4>Cross-sectional study in older adults aged 50 and over on ART attending an outpatient HIV/AIDS care centre in Uganda. Demographic and clinical data collected on number and type of medications plus supplements, possible medication related side-effects, comorbidity, frailty, cognitive impairment, current CD4 count and viral load.<h4>Results</h4>Of 411 participants, 63 (15.3, 95% C.I. 11.9, 18.8) had polypharmacy (≥ 4 non- HIV medications). In mBMC geriatrics125https://www.ebi.ac.uk/biostudies/studies/S-EPMC5975487biostudies-literaturePolypharmacy among HIV positive older adults on anti-retroviral therapy attending an urban clinic in Uganda.PMC5975487Stanaway FNamuleme TCumming RSsonko MKaramagi YMukasa BMayanja HKKyalimpa JLNaganathan VfalsePolypharmacy among HIV positive older adults on anti-retroviral therapy attending an urban clinic in Uganda.<h4>Background</h4>Polypharmacy has not been investigated in patients living with HIV in developing countries. The aims of this study were to determine the prevalence of polypharmacy, the factors associated with polypharmacy and whether polypharmacy was associated with adverse effects among older adults on anti-retroviral therapy (ART).<h4>Methods</h4>Cross-sectional study in older adults aged 50 and over on ART attending an outpatient HIV/AIDS care centre in Uganda. Demographic and clinical data collected on number and type of medications plus supplements, possible medication related side-effects, comorbidity, frailty, cognitive impairment, current CD4 count and viral load.<h4>Results</h4>Of 411 participants, 63 (15.3, 95% C.I. 11.9, 18.8) had polypharmacy (≥ 4 non- HIV medications). In m2018-01-01T00:00:00Z2018 May2025-04-18T17:31:51.409Z2019-03-26T23:39:39ZS-EPMC59754872984363510.1186/s12877-018-0817-0