{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lambert MA"],"funding":["Chest Heart and Stroke Scotland","Tenovus","Wellcome Trust"],"pagination":["795-804"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5979784"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["287(3)"],"pubmed_abstract":["Purpose To quantify the burden and distribution of asymptomatic atherosclerosis in a population with a low to intermediate risk of cardiovascular disease. Materials and Methods Between June 2008 and February 2013, 1528 participants with 10-year risk of cardiovascular disease less than 20% were prospectively enrolled. They underwent whole-body magnetic resonance (MR) angiography at 3.0 T by using a two-injection, four-station acquisition technique. Thirty-one arterial segments were scored according to maximum stenosis. Scores were summed and normalized for the number of assessable arterial segments to provide a standardized atheroma score (SAS). Multiple linear regression was performed to assess effects of risk factors on atheroma burden. Results A total of 1513 participants (577 [37.9%] me"],"journal":["Radiology"],"pubmed_title":["Prevalence and Distribution of Atherosclerosis in a Low- to Intermediate-Risk Population: Assessment with Whole-Body MR Angiography."],"pmcid":["PMC5979784"],"funding_grant_id":["WT 085664"],"pubmed_authors":["Belch JJF","Lambert MA","Levin D","White RD","Houston JG","Littleford R","Struthers AD","Sullivan F","Salsano M","Cavin I","Gandy SJ","MacFarlane JA","Henderson SA","Nicholas RS","Weir-McCall JR","Matthew SZ"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and Distribution of Atherosclerosis in a Low- to Intermediate-Risk Population: Assessment with Whole-Body MR Angiography.","description":"Purpose To quantify the burden and distribution of asymptomatic atherosclerosis in a population with a low to intermediate risk of cardiovascular disease. Materials and Methods Between June 2008 and February 2013, 1528 participants with 10-year risk of cardiovascular disease less than 20% were prospectively enrolled. They underwent whole-body magnetic resonance (MR) angiography at 3.0 T by using a two-injection, four-station acquisition technique. Thirty-one arterial segments were scored according to maximum stenosis. Scores were summed and normalized for the number of assessable arterial segments to provide a standardized atheroma score (SAS). Multiple linear regression was performed to assess effects of risk factors on atheroma burden. Results A total of 1513 participants (577 [37.9%] me","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jun","modification":"2025-04-26T08:27:46.143Z","creation":"2019-03-26T23:39:45Z"},"accession":"S-EPMC5979784","cross_references":{"pubmed":["29714681"],"doi":["10.1148/radiol.2018171609"]}}