biostudies-literatureOliveira FMFundação de Amparo à Pesquisa do Estado de GoiásConselho Nacional de Desenvolvimento Científico e Tecnológico1072https://www.ebi.ac.uk/biostudies/studies/S-EPMC5992710biostudies-literatureUnknown9<i>Mycobacterium abscessus</i> complex has been characterized in the last decade as part of a cluster of mycobacteria that evolved from an opportunistic to true human pathogen; however, the factors responsible for pathogenicity are still undefined. It appears that the success of mycobacterial infection is intrinsically related with the capacity of the bacteria to regulate intracellular iron levels, mostly using iron storage proteins. This study evaluated two potential <i>M. abscessus</i> subsp. <i>massiliense</i> genes involved in iron storage. Unlike other opportunist or pathogenic mycobacteria studied, <i>M. abscessus</i> complex has two genes similar to ferritins from <i>M. tuberculosis</i> (Rv3841), and in <i>M. abscessus</i> subsp. <i>massiliense</i>, those genes are annotated as <i>mFrontiers in microbiology<i>Mycobacterium abscessus</i> subsp. <i>massiliense mycma_0076</i> and <i>mycma_0077</i> Genes Code for Ferritins That Are Modulated by Iron Concentration.PMC5992710303675/2015-22012/0267000-482013/10267000-46).307186/2013-0;Da Costa ACKipnis AJunqueira-Kipnis APProcopio VOGarcia WDa Silva RAAraujo JNOliveira FMfalse<i>Mycobacterium abscessus</i> subsp. <i>massiliense mycma_0076</i> and <i>mycma_0077</i> Genes Code for Ferritins That Are Modulated by Iron Concentration.<i>Mycobacterium abscessus</i> complex has been characterized in the last decade as part of a cluster of mycobacteria that evolved from an opportunistic to true human pathogen; however, the factors responsible for pathogenicity are still undefined. It appears that the success of mycobacterial infection is intrinsically related with the capacity of the bacteria to regulate intracellular iron levels, mostly using iron storage proteins. This study evaluated two potential <i>M. abscessus</i> subsp. <i>massiliense</i> genes involved in iron storage. Unlike other opportunist or pathogenic mycobacteria studied, <i>M. abscessus</i> complex has two genes similar to ferritins from <i>M. tuberculosis</i> (Rv3841), and in <i>M. abscessus</i> subsp. <i>massiliense</i>, those genes are annotated as <i>m2018-01-01T00:00:00Z20182025-04-21T20:30:58.741Z2019-03-26T23:42:14ZS-EPMC59927102991077710.3389/fmicb.2018.01072