{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["54(2)"],"submitter":["Sediene S"],"pubmed_abstract":["Background and objectives: The importance of induction chemotherapy (ICT) followed by concurrent chemoradiotherapy (CCRT) has been re-established in recent years aiming at fewer metastatic sites and better control of the disease. We prospectively studied the possibility of early prediction of overall survival (OS) and progression-free survival (PFS) after 3 cycles of chemotherapy with doxetacel, cisplatin and 5-fluorouracil using 18-fluoro-2-deoxy-glucose positron emission tomography computed tomography (18F-FDG PET/CT) in patients with head and neck squamous cell cancer. To our knowledge, this is the first such study. Materials and Methods: Thirty-five patients were studied. They underwent an 18F-FDG PET/CT examination twice: a day before ICT and 10⁻14 days after the last cycle of ICT. Tu"],"journal":["Medicina (Kaunas, Lithuania)"],"pagination":["E31"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6037264"],"repository":["biostudies-literature"],"pubmed_title":["The Role of 18-Fluoro-2-Deoxy-Glucose Positron Emission Tomography/Computed Tomography as Response and Prognosis Predictive Factor of Concurrent Chemoradiotherapy after Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma: A Prospective Study."],"pmcid":["PMC6037264"],"pubmed_authors":["Ambraziene R","Rudzianskas V","Kulakiene I","Sediene S"],"additional_accession":[]},"is_claimable":false,"name":"The Role of 18-Fluoro-2-Deoxy-Glucose Positron Emission Tomography/Computed Tomography as Response and Prognosis Predictive Factor of Concurrent Chemoradiotherapy after Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma: A Prospective Study.","description":"Background and objectives: The importance of induction chemotherapy (ICT) followed by concurrent chemoradiotherapy (CCRT) has been re-established in recent years aiming at fewer metastatic sites and better control of the disease. We prospectively studied the possibility of early prediction of overall survival (OS) and progression-free survival (PFS) after 3 cycles of chemotherapy with doxetacel, cisplatin and 5-fluorouracil using 18-fluoro-2-deoxy-glucose positron emission tomography computed tomography (18F-FDG PET/CT) in patients with head and neck squamous cell cancer. To our knowledge, this is the first such study. Materials and Methods: Thirty-five patients were studied. They underwent an 18F-FDG PET/CT examination twice: a day before ICT and 10⁻14 days after the last cycle of ICT. Tu","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 May","modification":"2025-04-22T12:47:51.054Z","creation":"2019-03-27T00:04:24Z"},"accession":"S-EPMC6037264","cross_references":{"pubmed":["30344262"],"doi":["10.3390/medicina54020031"]}}