{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2(8)"],"submitter":["Stiefel C"],"pubmed_abstract":["Facing the widespread use of cosmetic products in daily use and recognizing the very limited information obtained by target analysis, a method suited for comprehensive characterization of cosmetics was aimed at. The biological activity of ingredients of 20 cosmetics taken from 16 different product groups and their coumarin contents were investigated via chromatography linked to bioassays (direct bioautography) and mass spectrometry. It allows for screening a large number of cosmetic products within a short time to generate a more valid database on their coumarin content and their contribution to the overall exposure. Bioactivity profiling of cosmetics with regard to bioactive ingredients opens new avenues for a comprehensive characterization of important substances in products of daily use"],"journal":["ACS omega"],"pagination":["5242-5250"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6044641"],"repository":["biostudies-literature"],"pubmed_title":["Bioprofiling of Cosmetics with Focus on Streamlined Coumarin Analysis."],"pmcid":["PMC6044641"],"pubmed_authors":["Morlock GE","Stiefel C","Schubert T"],"additional_accession":[]},"is_claimable":false,"name":"Bioprofiling of Cosmetics with Focus on Streamlined Coumarin Analysis.","description":"Facing the widespread use of cosmetic products in daily use and recognizing the very limited information obtained by target analysis, a method suited for comprehensive characterization of cosmetics was aimed at. The biological activity of ingredients of 20 cosmetics taken from 16 different product groups and their coumarin contents were investigated via chromatography linked to bioassays (direct bioautography) and mass spectrometry. It allows for screening a large number of cosmetic products within a short time to generate a more valid database on their coumarin content and their contribution to the overall exposure. Bioactivity profiling of cosmetics with regard to bioactive ingredients opens new avenues for a comprehensive characterization of important substances in products of daily use","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2025-05-29T20:27:40.868Z","creation":"2019-03-26T23:47:00Z"},"accession":"S-EPMC6044641","cross_references":{"pubmed":["30023744"],"doi":["10.1021/acsomega.7b00562"]}}