{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["3(1)"],"submitter":["Mallick T"],"pubmed_abstract":["The visible fluorescent chromophoric moiety present in the water-soluble photoactive yellow protein (PYP) of <i>Ectothiorhodospira halophila</i> is <i>p</i>-hydroxycinnamic acid linked to the cysteine residue (Cys-69) by a thioester bond and it controls the key photoinduced biological processes of the host organism. In the present work, we have synthesized and characterized three structurally different thiophenyl esters [viz., <i>p-</i>hydroxycinnamic-thiophenyl ester (<b>1</b>), <i>p</i>-<i>N</i>,<i>N</i>-dimethylaminocinnamic-thiophenyl ester (<b>2</b>), and <i>S</i>-phenyl-3-(4-chlorophenyl)-3-(phenylthio)propanethioate (<b>3</b>)] in addition to a novel (to the best of our knowledge) stilbene-type olefinic compound, <i>N</i><sup>1</sup>,<i>N</i><sup>1</sup>,<i>N</i><sup>2</sup>,<i>N</i"],"journal":["ACS omega"],"pagination":["334-348"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6044905"],"repository":["biostudies-literature"],"pubmed_title":["Fluorescent Small Molecules Are BIG Enough To Sense Biomacromolecule: Synthesis of Aromatic Thioesters and Understanding Their Interactions with ctDNA."],"pmcid":["PMC6044905"],"pubmed_authors":["Ahamed G","Batuta S","Alam MN","Mandal D","Das S","Mukherjee M","Das N","Karmakar A","Mallick T","Begum NA"],"additional_accession":[]},"is_claimable":false,"name":"Fluorescent Small Molecules Are BIG Enough To Sense Biomacromolecule: Synthesis of Aromatic Thioesters and Understanding Their Interactions with ctDNA.","description":"The visible fluorescent chromophoric moiety present in the water-soluble photoactive yellow protein (PYP) of <i>Ectothiorhodospira halophila</i> is <i>p</i>-hydroxycinnamic acid linked to the cysteine residue (Cys-69) by a thioester bond and it controls the key photoinduced biological processes of the host organism. In the present work, we have synthesized and characterized three structurally different thiophenyl esters [viz., <i>p-</i>hydroxycinnamic-thiophenyl ester (<b>1</b>), <i>p</i>-<i>N</i>,<i>N</i>-dimethylaminocinnamic-thiophenyl ester (<b>2</b>), and <i>S</i>-phenyl-3-(4-chlorophenyl)-3-(phenylthio)propanethioate (<b>3</b>)] in addition to a novel (to the best of our knowledge) stilbene-type olefinic compound, <i>N</i><sup>1</sup>,<i>N</i><sup>1</sup>,<i>N</i><sup>2</sup>,<i>N</i","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jan","modification":"2026-04-29T22:59:58.467Z","creation":"2019-03-26T23:47:15Z"},"accession":"S-EPMC6044905","cross_references":{"pubmed":["30023778"],"doi":["10.1021/acsomega.7b01933"]}}