biostudies-literatureLopez-Hidalgo CMinisterio de Economía y Competitividad935https://www.ebi.ac.uk/biostudies/studies/S-EPMC6050436biostudies-literatureUnknown9Holm oak (<i>Quercus ilex</i>) is the most important and representative species of the Mediterranean forest and of the Spanish agrosilvo-pastoral "dehesa" ecosystem. Despite its environmental and economic interest, Holm oak is an orphan species whose biology is very little known, especially at the molecular level. In order to increase the knowledge on the chemical composition and metabolism of this tree species, the employment of a holistic and multi-omics approach, in the Systems Biology direction would be necessary. However, for orphan and recalcitrant plant species, specific analytical and bioinformatics tools have to be developed in order to obtain adequate quality and data-density before to coping with the study of its biology. By using a plant sample consisting of a pool generated byFrontiers in plant scienceA Multi-Omics Analysis Pipeline for the Metabolic Pathway Reconstruction in the Orphan Species <i>Quercus ilex</i>.PMC6050436BIO2015-64737-RCastillejo-Sanchez MALopez-Hidalgo CValledor LJorrin-Novo JVGomez-Galvez IMaldonado-Alconada AMGuerrero-Sanchez VMSanchez-Lucas RfalseA Multi-Omics Analysis Pipeline for the Metabolic Pathway Reconstruction in the Orphan Species <i>Quercus ilex</i>.Holm oak (<i>Quercus ilex</i>) is the most important and representative species of the Mediterranean forest and of the Spanish agrosilvo-pastoral "dehesa" ecosystem. Despite its environmental and economic interest, Holm oak is an orphan species whose biology is very little known, especially at the molecular level. In order to increase the knowledge on the chemical composition and metabolism of this tree species, the employment of a holistic and multi-omics approach, in the Systems Biology direction would be necessary. However, for orphan and recalcitrant plant species, specific analytical and bioinformatics tools have to be developed in order to obtain adequate quality and data-density before to coping with the study of its biology. By using a plant sample consisting of a pool generated by2018-01-01T00:00:00Z20182026-04-07T20:02:56.445Z2019-03-26T23:48:13ZS-EPMC60504363005054410.3389/fpls.2018.00935