{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2018"],"submitter":["Naf G"],"funding":["Kantonsspital Graubünden"],"pubmed_abstract":["<h4>Background</h4>To assess effectiveness of NPE, a proprietary Camellia sinensis nonfermentatum (CSNF) extract, in prevention and recovery of acute radiation-induced skin reaction (ARSR) and skin care during postoperative whole breast radiotherapy (RT).<h4>Methods</h4>Twenty patients were enrolled in this single centre, prospective, open-label pilot study. The outcomes of 20 prospective data sets were compared with 100 retrospectively collected matched data sets derived from hospital records. The preventive CSNF gel (2.5%) was administered 1 to 2 hours before each session on the irradiated fields. The care CSNF lotion (0.4%) was administered as 7-day pretreatment after each RT session, twice daily between RT sessions, and 4 to 8 weeks thereafter. The control group was treated according t"],"journal":["International journal of breast cancer"],"pagination":["2479274"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6051114"],"repository":["biostudies-literature"],"pubmed_title":["Prevention of Acute Radiation-Induced Skin Reaction with NPE® Camellia Sinensis Nonfermentatum Extract in Female Breast Cancer Patients Undergoing Postoperative Radiotherapy: A Single Centre, Prospective, Open-Label Pilot Study."],"pmcid":["PMC6051114"],"pubmed_authors":["Oehler C","Naf G","Gasser UE","Schafroth S","Zwahlen DR","Holzgang HE"],"additional_accession":[]},"is_claimable":false,"name":"Prevention of Acute Radiation-Induced Skin Reaction with NPE® Camellia Sinensis Nonfermentatum Extract in Female Breast Cancer Patients Undergoing Postoperative Radiotherapy: A Single Centre, Prospective, Open-Label Pilot Study.","description":"<h4>Background</h4>To assess effectiveness of NPE, a proprietary Camellia sinensis nonfermentatum (CSNF) extract, in prevention and recovery of acute radiation-induced skin reaction (ARSR) and skin care during postoperative whole breast radiotherapy (RT).<h4>Methods</h4>Twenty patients were enrolled in this single centre, prospective, open-label pilot study. The outcomes of 20 prospective data sets were compared with 100 retrospectively collected matched data sets derived from hospital records. The preventive CSNF gel (2.5%) was administered 1 to 2 hours before each session on the irradiated fields. The care CSNF lotion (0.4%) was administered as 7-day pretreatment after each RT session, twice daily between RT sessions, and 4 to 8 weeks thereafter. The control group was treated according t","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2025-05-31T22:35:59.234Z","creation":"2025-05-31T22:35:59.234Z"},"accession":"S-EPMC6051114","cross_references":{"pubmed":["30057821"],"doi":["10.1155/2018/2479274"]}}