biostudies-literaturePlomion CEuropean Research Council440-452https://www.ebi.ac.uk/biostudies/studies/S-EPMC6086335biostudies-literatureUnknown4(7)Oaks are an important part of our natural and cultural heritage. Not only are they ubiquitous in our most common landscapes¹ but they have also supplied human societies with invaluable services, including food and shelter, since prehistoric times². With 450 species spread throughout Asia, Europe and America³, oaks constitute a critical global renewable resource. The longevity of oaks (several hundred years) probably underlies their emblematic cultural and historical importance. Such long-lived sessile organisms must persist in the face of a wide range of abiotic and biotic threats over their lifespans. We investigated the genomic features associated with such a long lifespan by sequencing, assembling and annotating the oak genome. We then used the growing nNature plantsOak genome reveals facets of long lifespan.PMC6086335339728Dossat CSalin FBelser CLuyten IDuplessis SChancerel EMartin FFrancillonne NDesprez-Loustau MLGaspin CMurat FFaye SHerrmann SFaivre-Rampant PBodenes CLasserre EChantret NHummel IMadoui MAPicault NChen JDievart ALascoux MRue OMangenot SEhrenmann FTarkka MGrima-Pettenati JLeroy TSoler MQuesneville HLesur IKlopp CPlomion CLeple JCMaumus FAmselem JBrachi BWincker PAlaeitabar TDa Silva CZanne AECouloux ALe Provost GBouffaud MLMichotey CRustenholz CPanaud ORouhier NGuichoux EBerges HSalse JLabadie KMercier JAury JMKohler ALalanne CMarchal CLemainque ABarbe VBogeat-Triboulot MBVelt AKremer ACohen DBartholome JHecker AHugueney PfalseOak genome reveals facets of long lifespan.Oaks are an important part of our natural and cultural heritage. Not only are they ubiquitous in our most common landscapes¹ but they have also supplied human societies with invaluable services, including food and shelter, since prehistoric times². With 450 species spread throughout Asia, Europe and America³, oaks constitute a critical global renewable resource. The longevity of oaks (several hundred years) probably underlies their emblematic cultural and historical importance. Such long-lived sessile organisms must persist in the face of a wide range of abiotic and biotic threats over their lifespans. We investigated the genomic features associated with such a long lifespan by sequencing, assembling and annotating the oak genome. We then used the growing n2018-01-01T00:00:00Z2018 Jul2026-05-02T08:51:38.759Z2019-03-26T22:28:44ZS-EPMC60863352991533110.1038/s41477-018-0172-3