{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bompas E"],"funding":["Ligue de L'Ain contre le Cancer, LYric","la Fondation ARC, Infosarcome, InterSARC (INCA), LabEx DEvweCAN","RREPS (INCA)","NetSARC (INCA)","Association DAM's, Ensemble contre Le GIST, Eurosarc"],"pagination":["4023-4035"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6089183"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(8)"],"pubmed_abstract":["Five-year overall survival (OS) of localized RMS exceeds 70% in children (<18) but is very poor in adult patients. We analyzed the outcome and prognostic factors (PF) of a national series of adult patients with RMS in a large study. The study population consisted of two different cohorts: a retrospective cohort (157 adult patients treated in 13 reference centers between 05/1981 and 02/2010) and the prospective cohort (292 patients with RMS diagnosed and treated between 01/2010 and 12/2014 in France) included in the NetSarc database. A descriptive analysis of patients' characteristics and prognostic factors was conducted on both series which were compared. In the retrospective series, histological subtypes were embryonal (E-RMS) for 21% of patients, alveolar (A-RMS) for 35% of patients, and"],"journal":["Cancer medicine"],"pubmed_title":["Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study."],"pmcid":["PMC6089183"],"funding_grant_id":["ANR-10-LABX-0061","FP7-278742","DGOS-INCa-4664"],"pubmed_authors":["Piperno-Neumann S","Soulie P","Chevreau C","Isambert N","Rios M","Karanian M","Penel N","Mir O","Duffaud F","Italiano A","Ray-Coquard I","Campion L","Saada-Bouzid E","Le Cesne A","Delcambre C","Blay JY","Kurtz JE","Dubray-Longeras P","Le Loarer F","Bompas E","Toulmonde M"],"additional_accession":[]},"is_claimable":false,"name":"Outcome of 449 adult patients with rhabdomyosarcoma: an observational ambispective nationwide study.","description":"Five-year overall survival (OS) of localized RMS exceeds 70% in children (<18) but is very poor in adult patients. We analyzed the outcome and prognostic factors (PF) of a national series of adult patients with RMS in a large study. The study population consisted of two different cohorts: a retrospective cohort (157 adult patients treated in 13 reference centers between 05/1981 and 02/2010) and the prospective cohort (292 patients with RMS diagnosed and treated between 01/2010 and 12/2014 in France) included in the NetSarc database. A descriptive analysis of patients' characteristics and prognostic factors was conducted on both series which were compared. In the retrospective series, histological subtypes were embryonal (E-RMS) for 21% of patients, alveolar (A-RMS) for 35% of patients, and","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Aug","modification":"2025-04-21T14:52:54.527Z","creation":"2019-03-26T23:51:38Z"},"accession":"S-EPMC6089183","cross_references":{"pubmed":["29956493"],"doi":["10.1002/cam4.1374"]}}