{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["55(9)"],"submitter":["McCuaig JM"],"pubmed_abstract":["The landscape of genetic testing in ovarian cancer patients has changed dramatically in recent years. The therapeutic benefits of poly ADP-ribose polymerase (PARP) inhibitors in treatment of <i>BRCA1/2</i>-related ovarian cancers has resulted in an increased demand and urgency for genetic testing results, while technological developments have led to widespread use of multi-gene cancer panels and development of tumour testing protocols. Traditional genetic counselling models are no longer sustainable and must evolve to match the rapid evolution of genetic testing technologies and developments in personalized medicine. Recently, representatives from oncology, clinical genetics, molecular genetics, pathology, and patient advocacy came together to create a national multi-disciplinary Canadian "],"journal":["Journal of medical genetics"],"pagination":["571-577"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6119348"],"repository":["biostudies-literature"],"pubmed_title":["Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap."],"pmcid":["PMC6119348"],"pubmed_authors":["Kieser K","Lapointe-Milot K","Hawrysh A","Young SS","Grafodatskaya D","Stockley TL","Macmillan A","Sun S","Cormier B","Baines KA","Speevak M","Sadikovic B","Hirte H","Dawson L","Lo B","Chong G","Farag M","Bernardini MQ","Tonkin K","Zeng Z","Serfas K","Stockley T","Perrier R","Mcgee J","Kim RH","Provencher D","Young S","Meschino WS","Fung-Kee-Fung M","McCuaig JM","Baugh E","Giede C","Altman AD","Chodirker B","BRCA TtoT Community of Practice","Power P","Thomas H","Gotlieb W","MacMillan A","Ghatage P","Shaw P","Kotsopoulos JG","Penney L","Power J","Dornan K","Grover K","Miller D","Baret L","Wong N","Somerville M","Hoskins P","Foulkes W","Mccuaig J","Panabaker K","Vaags A","Bernardini M","Salvador S","Smith A","Schrader KA","Vandersteen A","Green J","Mcgowan-Jordan J","Tomiak E","Kamel-Reid S","Lau S","Samouelian V","Metcalfe K","Mccready E","Kim R","Gotlieb WH","Schindeler K","Djordjevic B","Meschino W","Bentley J","Altman A"],"additional_accession":[]},"is_claimable":false,"name":"Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap.","description":"The landscape of genetic testing in ovarian cancer patients has changed dramatically in recent years. The therapeutic benefits of poly ADP-ribose polymerase (PARP) inhibitors in treatment of <i>BRCA1/2</i>-related ovarian cancers has resulted in an increased demand and urgency for genetic testing results, while technological developments have led to widespread use of multi-gene cancer panels and development of tumour testing protocols. Traditional genetic counselling models are no longer sustainable and must evolve to match the rapid evolution of genetic testing technologies and developments in personalized medicine. Recently, representatives from oncology, clinical genetics, molecular genetics, pathology, and patient advocacy came together to create a national multi-disciplinary Canadian ","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Sep","modification":"2026-06-14T06:04:54.915Z","creation":"2026-06-14T03:16:47.8Z"},"accession":"S-EPMC6119348","cross_references":{"pubmed":["30042185"],"doi":["10.1136/jmedgenet-2018-105472"]}}