biostudies-literatureUnknown24(47)Witteman LA computationally guided synthetic route to a free silanide derived from tris(3-methylindol-2-yl)methane ([(tmim)Si]^- ) through nucleophilic substitution on the Si^II precursor (Idipp)SiCl₂ is reported (Idipp=2,3-dihydro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-ylidene). This approach circumvents the need for strained tetrahedral silanes as synthetic intermediates. Computational investigations show that the electron-donating properties of [(tmim)Si]^- are close to those of PMe_3. Experimentally, the [(tmim)Si]^- anion is shown to undergo clean complexation to the base metal salts CuCl and FeCl₂ , demonstrating the potential utility as a supporting ligand.Chemistry (Weinheim an der Bergstrasse, Germany)12236-12240https://www.ebi.ac.uk/biostudies/studies/S-EPMC6120461biostudies-literatureA Free Silanide from Nucleophilic Substitution at Silicon(II).PMC6120461Moret MEEvers TWitteman LLutz MfalseA Free Silanide from Nucleophilic Substitution at Silicon(II).A computationally guided synthetic route to a free silanide derived from tris(3-methylindol-2-yl)methane ([(tmim)Si]^- ) through nucleophilic substitution on the Si^II precursor (Idipp)SiCl₂ is reported (Idipp=2,3-dihydro-1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-ylidene). This approach circumvents the need for strained tetrahedral silanes as synthetic intermediates. Computational investigations show that the electron-donating properties of [(tmim)Si]^- are close to those of PMe_3. Experimentally, the [(tmim)Si]^- anion is shown to undergo clean complexation to the base metal salts CuCl and FeCl₂ , demonstrating the potential utility as a supporting ligand.2018-01-01T00:00:00Z2018 Aug2021-02-21T07:46:21Z2019-03-26T23:54:48ZS-EPMC61204612957749110.1002/chem.201801435