{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(8)"],"submitter":["Moretti R"],"pubmed_abstract":["It is widely known that vitamin D receptors have been found in neurons and glial cells, and their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical grey nuclei, and substantia nigra. Vitamin D helps the regulation of neurotrophin, neural differentiation, and maturation, through the control operation of growing factors synthesis (i.e., neural growth factor [NGF] and glial cell line-derived growth factor (GDNF), the trafficking of the septohippocampal pathway, and the control of the synthesis process of different neuromodulators (such as acetylcholine [Ach], dopamine [DA], and gamma-aminobutyric [GABA]). Based on these assumptions, we have written this review to summarize the potential role of vitamin D in neurological pathologies. This work could be titanic an"],"journal":["International journal of molecular sciences"],"pagination":["E2245"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6121649"],"repository":["biostudies-literature"],"pubmed_title":["Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact."],"pmcid":["PMC6121649"],"pubmed_authors":["Moretti R","Caruso P","Morelli ME"],"additional_accession":[]},"is_claimable":false,"name":"Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact.","description":"It is widely known that vitamin D receptors have been found in neurons and glial cells, and their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical grey nuclei, and substantia nigra. Vitamin D helps the regulation of neurotrophin, neural differentiation, and maturation, through the control operation of growing factors synthesis (i.e., neural growth factor [NGF] and glial cell line-derived growth factor (GDNF), the trafficking of the septohippocampal pathway, and the control of the synthesis process of different neuromodulators (such as acetylcholine [Ach], dopamine [DA], and gamma-aminobutyric [GABA]). Based on these assumptions, we have written this review to summarize the potential role of vitamin D in neurological pathologies. This work could be titanic an","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jul","modification":"2025-04-22T18:35:31.363Z","creation":"2019-03-26T23:54:53Z"},"accession":"S-EPMC6121649","cross_references":{"pubmed":["30065237"],"doi":["10.3390/ijms19082245"]}}