{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ruff A"],"funding":["Deutsche Forschungsgemeinschaft (German Research Foundation)","Agence Nationale de la Recherche (French National Research Agency)"],"pagination":["3675"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6131248"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(1)"],"pubmed_abstract":["Hydrogenases with Ni- and/or Fe-based active sites are highly active hydrogen oxidation catalysts with activities similar to those of noble metal catalysts. However, the activity is connected to a sensitivity towards high-potential deactivation and oxygen damage. Here we report a fully protected polymer multilayer/hydrogenase-based bioanode in which the sensitive hydrogen oxidation catalyst is protected from high-potential deactivation and from oxygen damage by using a polymer multilayer architecture. The active catalyst is embedded in a low-potential polymer (protection from high-potential deactivation) and covered with a polymer-supported bienzymatic oxygen removal system. In contrast to previously reported polymer-based protection systems, the proposed strategy fully decouples the hydrogenase reaction form the protection process. Incorporation of the bioanode into a hydrogen/glucose biofuel cell provides a benchmark open circuit voltage of 1.15?V and power densities of up to 530?µW?cm<sup>-2</sup> at 0.85?V."],"journal":["Nature communications"],"pubmed_title":["A fully protected hydrogenase/polymer-based bioanode for high-performance hydrogen/glucose biofuel cells."],"pmcid":["PMC6131248"],"funding_grant_id":["SHIELD","LU 315/17-1/2","EXC1069"],"pubmed_authors":["Schuhmann W","Markovic N","Pereira IAC","Conzuelo F","Lubitz W","Ruff A","Szczesny J","Zacarias S"],"additional_accession":[]},"is_claimable":false,"name":"A fully protected hydrogenase/polymer-based bioanode for high-performance hydrogen/glucose biofuel cells.","description":"Hydrogenases with Ni- and/or Fe-based active sites are highly active hydrogen oxidation catalysts with activities similar to those of noble metal catalysts. However, the activity is connected to a sensitivity towards high-potential deactivation and oxygen damage. Here we report a fully protected polymer multilayer/hydrogenase-based bioanode in which the sensitive hydrogen oxidation catalyst is protected from high-potential deactivation and from oxygen damage by using a polymer multilayer architecture. The active catalyst is embedded in a low-potential polymer (protection from high-potential deactivation) and covered with a polymer-supported bienzymatic oxygen removal system. In contrast to previously reported polymer-based protection systems, the proposed strategy fully decouples the hydrogenase reaction form the protection process. Incorporation of the bioanode into a hydrogen/glucose biofuel cell provides a benchmark open circuit voltage of 1.15?V and power densities of up to 530?µW?cm<sup>-2</sup> at 0.85?V.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Sep","modification":"2021-02-20T21:19:55Z","creation":"2019-03-26T23:58:16Z"},"accession":"S-EPMC6131248","cross_references":{"pubmed":["30202006"],"doi":["10.1038/s41467-018-06106-3"]}}