{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Karoyo AH"],"funding":["Natural Sciences and Engineering Research Council of Canada"],"pagination":["403"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6141685"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6"],"pubmed_abstract":["Dual function polymer materials with immobilized <i>Sphingobium Chorophenolicum</i> (SpC) bacterium cells are reported herein that undergo tandem adsorption and biodegradation of phenolic compounds. The cross-linked polymer materials contain β-cyclodextrin (β-CD) with incremental hexamethylene diisocyanate (HDI) cross-linker at variable mole ratios (X = 1, 3, or 6), denoted as HDI-X systems. The adsorptive uptake properties of the insoluble HDI-X polymers (X = 3 and 6) with various phenolic compounds [pentachlorophenol (PCP), 2,4,6-trichlorophenol (TCP), and 2,4,6-trimethylphenol (TMP)] were studied using batch adsorption isotherms. The molecular selective phenol removal (S<sub>R</sub>) capacity of the HDI-3 and HDI-6 materials was evaluated by electrospray ionization mass spectrometry (ESI-MS). The results were compared against granular activated carbon (GAC) and native β-CD, where 1D/2D <sup>1</sup>H NMR spectral characterization of the complexes formed between phenolic guests and a soluble polymer (HDI-1) in aqueous solution provide insight on the intermolecular interactions and the role of cross-linking effects. Immobilization of SpC onto HDI-3 was shown to form a composite polymer/bacterium material. The composite system displays synergistic removal effects due to tandem PCP adsorption and SpC biodegradation to yield by-products such as 2,6-dichloro-1,4-hydroquinone (DCHQ). Apoptosis and cytotoxicity of DCHQ were evaluated using three breast cancer cell lines."],"journal":["Frontiers in chemistry"],"pubmed_title":["Cyclodextrin-Based Polymer-Supported Bacterium for the Adsorption and <i>in-situ</i> Biodegradation of Phenolic Compounds."],"pmcid":["PMC6141685"],"funding_grant_id":["RGPIN 2016-06197"],"pubmed_authors":["Yang J","Karoyo AH","Wilson LD"],"additional_accession":[]},"is_claimable":false,"name":"Cyclodextrin-Based Polymer-Supported Bacterium for the Adsorption and <i>in-situ</i> Biodegradation of Phenolic Compounds.","description":"Dual function polymer materials with immobilized <i>Sphingobium Chorophenolicum</i> (SpC) bacterium cells are reported herein that undergo tandem adsorption and biodegradation of phenolic compounds. The cross-linked polymer materials contain β-cyclodextrin (β-CD) with incremental hexamethylene diisocyanate (HDI) cross-linker at variable mole ratios (X = 1, 3, or 6), denoted as HDI-X systems. The adsorptive uptake properties of the insoluble HDI-X polymers (X = 3 and 6) with various phenolic compounds [pentachlorophenol (PCP), 2,4,6-trichlorophenol (TCP), and 2,4,6-trimethylphenol (TMP)] were studied using batch adsorption isotherms. The molecular selective phenol removal (S<sub>R</sub>) capacity of the HDI-3 and HDI-6 materials was evaluated by electrospray ionization mass spectrometry (ESI-MS). The results were compared against granular activated carbon (GAC) and native β-CD, where 1D/2D <sup>1</sup>H NMR spectral characterization of the complexes formed between phenolic guests and a soluble polymer (HDI-1) in aqueous solution provide insight on the intermolecular interactions and the role of cross-linking effects. Immobilization of SpC onto HDI-3 was shown to form a composite polymer/bacterium material. The composite system displays synergistic removal effects due to tandem PCP adsorption and SpC biodegradation to yield by-products such as 2,6-dichloro-1,4-hydroquinone (DCHQ). Apoptosis and cytotoxicity of DCHQ were evaluated using three breast cancer cell lines.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-05-06T02:56:35.997Z","creation":"2025-05-18T13:24:04.938Z"},"accession":"S-EPMC6141685","cross_references":{"pubmed":["30255014"],"doi":["10.3389/fchem.2018.00403"]}}