{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jarett JK"],"funding":["U.S. Department of Energy","National Science Foundation"],"pagination":["161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6142677"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6(1)"],"pubmed_abstract":["<h4>Background</h4>Nanoarchaeota are obligate symbionts of other Archaea first discovered 16 years ago, yet little is known about this largely uncultivated taxon. While Nanoarchaeota diversity has been detected in a variety of habitats using 16S rRNA gene surveys, genome sequences have been available for only three Nanoarchaeota and their hosts. The host range and adaptation of Nanoarchaeota to a wide range of environmental conditions has thus largely remained elusive. Single-cell genomics is an ideal approach to address these questions as Nanoarchaeota can be isolated while still attached to putative hosts, enabling the exploration of cell-cell interactions and fine-scale genomic diversity.<h4>Results</h4>From 22 single amplified genomes (SAGs) from three hot springs in Yellowstone Nation"],"journal":["Microbiome"],"pubmed_title":["Single-cell genomics of co-sorted Nanoarchaeota suggests novel putative host associations and diversification of proteins involved in symbiosis."],"pmcid":["PMC6142677"],"funding_grant_id":["DE-AC02-05CH11231","DEB-1441717","OCe-1335810"],"pubmed_authors":["Malmstrom RR","Jarett JK","Nayfach S","Podar M","Stepanauskas R","Beam JP","Kyrpides NC","Inskeep W","Woyke T","Ivanova NN","Schulz F","Jay ZJ","Young M","Munson-McGee J"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell genomics of co-sorted Nanoarchaeota suggests novel putative host associations and diversification of proteins involved in symbiosis.","description":"<h4>Background</h4>Nanoarchaeota are obligate symbionts of other Archaea first discovered 16 years ago, yet little is known about this largely uncultivated taxon. While Nanoarchaeota diversity has been detected in a variety of habitats using 16S rRNA gene surveys, genome sequences have been available for only three Nanoarchaeota and their hosts. The host range and adaptation of Nanoarchaeota to a wide range of environmental conditions has thus largely remained elusive. Single-cell genomics is an ideal approach to address these questions as Nanoarchaeota can be isolated while still attached to putative hosts, enabling the exploration of cell-cell interactions and fine-scale genomic diversity.<h4>Results</h4>From 22 single amplified genomes (SAGs) from three hot springs in Yellowstone Nation","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Sep","modification":"2026-06-06T20:41:26.967Z","creation":"2019-03-26T23:56:49Z"},"accession":"S-EPMC6142677","cross_references":{"pubmed":["30223889"],"doi":["10.1186/s40168-018-0539-8"]}}