{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Torkova AA"],"funding":["Russian Science Foundation"],"pagination":["e0204261"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6147495"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(9)"],"pubmed_abstract":["The physicochemical characteristics and functional properties of pumpkin (Cucurbita maxima D. var. Cabello de Ángel) pectin obtained by cavitation facilitated extraction from pumpkin pulp have been evaluated and compared with commercial citrus and apple pectins. C. maxima pectin had an Mw value of 90 kDa and a high degree (72%) of esterification. The cytoprotective and antioxidant effects of citrus, apple and pumpkin pectin samples with different concentrations were studied in vitro in cell lines HT-29 (human colon adenocarcinoma) and MDCK1 (canine kidney epithelium). All pectin samples exhibited cytoprotective effect in HT-29 and MDCK1 cells after incubation with toxic concentrations of cadmium and mercury for 4 h. Pumpkin pectin increased the proliferation of cadmium-treated MDCK1 cells "],"journal":["PloS one"],"pubmed_title":["Physicochemical and functional properties of Cucurbita maxima pumpkin pectin and commercial citrus and apple pectins: A comparative evaluation."],"pmcid":["PMC6147495"],"funding_grant_id":["16-16-00094"],"pubmed_authors":["Torkova AA","Glazunova OA","Golubev VN","Lisitskaya KV","Kachalova GS","Fedorova TV","Filimonov IS"],"additional_accession":[]},"is_claimable":false,"name":"Physicochemical and functional properties of Cucurbita maxima pumpkin pectin and commercial citrus and apple pectins: A comparative evaluation.","description":"The physicochemical characteristics and functional properties of pumpkin (Cucurbita maxima D. var. Cabello de Ángel) pectin obtained by cavitation facilitated extraction from pumpkin pulp have been evaluated and compared with commercial citrus and apple pectins. C. maxima pectin had an Mw value of 90 kDa and a high degree (72%) of esterification. The cytoprotective and antioxidant effects of citrus, apple and pumpkin pectin samples with different concentrations were studied in vitro in cell lines HT-29 (human colon adenocarcinoma) and MDCK1 (canine kidney epithelium). All pectin samples exhibited cytoprotective effect in HT-29 and MDCK1 cells after incubation with toxic concentrations of cadmium and mercury for 4 h. Pumpkin pectin increased the proliferation of cadmium-treated MDCK1 cells ","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-04-28T03:23:16.336Z","creation":"2019-03-27T00:01:15Z"},"accession":"S-EPMC6147495","cross_references":{"pubmed":["30235297"],"doi":["10.1371/journal.pone.0204261"]}}