{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fomenky BE"],"funding":["Gouvernement du Canada | Agriculture and Agri-Food Canada","Gouvernement du Canada | Agriculture and Agri-Food Canada (Agriculture et Agroalimentaire Canada)"],"pagination":["14147"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6148029"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(1)"],"pubmed_abstract":["This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a control diet (CTL) supplemented with SCB or LA or ATB for 96 days. On day 33 (pre-weaning, n = 16) and day 96 (post-weaning, n = 16), digesta from the rumen, ileum, and colon, and mucosa from the ileum and colon were collected. The bacterial diversity and composition of the gastrointestinal tract (GIT) of pre- and post-weaned calves were characterized by sequencing the V3-V4 region of the bacterial 16S rRNA gene. The DFMs had significant impact on bacteria community structure with most changes associated with tr"],"journal":["Scientific reports"],"pubmed_title":["Direct-fed microbial supplementation influences the bacteria community composition of the gastrointestinal tract of pre- and post-weaned calves."],"pmcid":["PMC6148029"],"funding_grant_id":["J-000218"],"pubmed_authors":["Chiquette J","Ibeagha-Awemu EM","Lessard M","Talbot G","Bissonnette N","Chouinard YP","Fomenky BE","Do DN"],"additional_accession":[]},"is_claimable":false,"name":"Direct-fed microbial supplementation influences the bacteria community composition of the gastrointestinal tract of pre- and post-weaned calves.","description":"This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a control diet (CTL) supplemented with SCB or LA or ATB for 96 days. On day 33 (pre-weaning, n = 16) and day 96 (post-weaning, n = 16), digesta from the rumen, ileum, and colon, and mucosa from the ileum and colon were collected. The bacterial diversity and composition of the gastrointestinal tract (GIT) of pre- and post-weaned calves were characterized by sequencing the V3-V4 region of the bacterial 16S rRNA gene. The DFMs had significant impact on bacteria community structure with most changes associated with tr","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Sep","modification":"2026-06-17T06:12:18.386Z","creation":"2025-04-20T04:06:31.949Z"},"accession":"S-EPMC6148029","cross_references":{"pubmed":["30237565"],"doi":["10.1038/s41598-018-32375-5"]}}