biostudies-literatureNewton NCNational Health and Medical Research Council34https://www.ebi.ac.uk/biostudies/studies/S-EPMC6157057biostudies-literatureUnknown13(1)<h4>Background</h4>The Climate and Preventure (CAP) study was the first trial to assess and demonstrate the effectiveness of a combined universal and selective approach for preventing alcohol use and related harms among adolescents. The current paper reports universal effects from the CAP study on cannabis-related outcomes over three years.<h4>Methods</h4>A cluster randomized controlled trial was conducted with 2190 students from twenty-six Australian high schools (mean age: 13.3 yrs., SD 0.48). Participants were randomised to one of four conditions; universal prevention for all students (Climate); selective prevention for high-risk students (Preventure); combined universal and selective prevention (Climate and Preventure; CAP); or health education as usual (Control). Participants were assSubstance abuse treatment, prevention, and policyUniversal cannabis outcomes from the Climate and Preventure (CAP) study: a cluster randomised controlled trial.PMC6157057APP1870487APP1056432APP1004744APP1041129Mather MStapinski LNewton NCChampion KEKelly ETeesson MCarragher NBarrett ELSlade TConrod PJfalseUniversal cannabis outcomes from the Climate and Preventure (CAP) study: a cluster randomised controlled trial.<h4>Background</h4>The Climate and Preventure (CAP) study was the first trial to assess and demonstrate the effectiveness of a combined universal and selective approach for preventing alcohol use and related harms among adolescents. The current paper reports universal effects from the CAP study on cannabis-related outcomes over three years.<h4>Methods</h4>A cluster randomized controlled trial was conducted with 2190 students from twenty-six Australian high schools (mean age: 13.3 yrs., SD 0.48). Participants were randomised to one of four conditions; universal prevention for all students (Climate); selective prevention for high-risk students (Preventure); combined universal and selective prevention (Climate and Preventure; CAP); or health education as usual (Control). Participants were ass2018-01-01T00:00:00Z2018 Sep2025-04-04T11:20:53.171Z2019-03-26T23:57:33ZS-EPMC61570573025379010.1186/s13011-018-0171-4