biostudies-literatureWoods-Townsend KBritish Heart FoundationMedical Research CouncilNational Institute for Health Research (NIHR)475-480https://www.ebi.ac.uk/biostudies/studies/S-EPMC6159871biostudies-literatureUnknown9(5)Adolescence is a critical time point in the lifecourse. LifeLab is an educational intervention engaging adolescents in understanding Developmental Origins of Health and Disease (DOHaD) concepts and the impact of the early life environment on future health, benefitting both their long-term health and that of the next generation. We aimed to assess whether engaging adolescents with DOHaD concepts improves scientific literacy and whether engagement alone improves health behaviours.Six schools were randomized, three to intervention and three to control. Outcome measures were changed in knowledge, and intended and actual behaviour in relation to diet and lifestyle. A total of 333 students completed baseline and follow-up questionnaires. At 12 months, intervention students showed greater understJournal of developmental origins of health and diseaseLifeLab Southampton: a programme to engage adolescents with DOHaD concepts as a tool for increasing health literacy in teenagers -a pilot cluster-randomized control trial.PMC6159871MC_UU_12011/4PG/14/33/30827RG/15/17/31749NF-SI-0515-10042Woods-Townsend KHanson MGodfrey KLeat HBagust LDavey HChristodoulou AGriffiths JInskip HBay JGrace MLovelock DfalseLifeLab Southampton: a programme to engage adolescents with DOHaD concepts as a tool for increasing health literacy in teenagers -a pilot cluster-randomized control trial.Adolescence is a critical time point in the lifecourse. LifeLab is an educational intervention engaging adolescents in understanding Developmental Origins of Health and Disease (DOHaD) concepts and the impact of the early life environment on future health, benefitting both their long-term health and that of the next generation. We aimed to assess whether engaging adolescents with DOHaD concepts improves scientific literacy and whether engagement alone improves health behaviours.Six schools were randomized, three to intervention and three to control. Outcome measures were changed in knowledge, and intended and actual behaviour in relation to diet and lifestyle. A total of 333 students completed baseline and follow-up questionnaires. At 12 months, intervention students showed greater underst2018-01-01T00:00:00Z2018 Oct2025-04-04T00:32:54.147Z2019-08-04T08:11:53ZS-EPMC61598713010173110.1017/S204017441800042910.1017/s2040174418000429