{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ali SA"],"funding":["the University of the Witwatersrand, the Medical Research Council, South Africa, and the Wellcome Trust, UK","INDEPTH Network in Accra, Ghana","AWI-Gen Collaborative Centre","FIC NIH HHS","Health and Aging Study in Africa","NHGRI NIH HHS","National Institutes of Health","Department of Science and Technology, South Africa","Wellcome Trust"],"pagination":["1507133"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6161608"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(sup2)"],"pubmed_abstract":["There is an alarming tide of cardiovascular and metabolic disease (CMD) sweeping across Africa. This may be a result of an increasingly urbanized lifestyle characterized by the growing consumption of processed and calorie-dense food, combined with physical inactivity and more sedentary behaviour. While the link between lifestyle and public health has been extensively studied in Caucasian and African American populations, few studies have been conducted in Africa. This paper describes the detailed methods for Phase 1 of the AWI-Gen study that were used to capture phenotype data and assess the associated risk factors and end points for CMD in persons over the age of 40 years in sub-Saharan Africa (SSA). We developed a population-based cross-sectional study of disease burden and phenotype in "],"journal":["Global health action"],"pubmed_title":["Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study."],"pmcid":["PMC6161608"],"funding_grant_id":["U54 HG006938","085477","085477/Z08/Z","058893","DST/CON 0056/2014","U54HG006938","P01 AG041710","058893/A/99A","U54HG006938-03S1","069683/Z/02/Z","K43 TW010698"],"pubmed_authors":["Mukomana F","Agongo G","Khayeka-Wandabwa C","Norris SA","Some AM","Ramsay M","Alberts M","Amenga-Etego L","Depuur C","Kyobutungi C","Soo C","Lombard Z","Mohamed SF","Oduro AR","Twine R","Gomez-Olive FX","Sorgho H","Nakanabo-Diallo S","Choudhury A","Natama HM","Tinto H","Tollman S","Kahn K","Boua RP","Guiraud I","Crowther NJ","Haregu TN","Tindana P","Wade A","Ngomi N","Hazelhurst S","Micklesfield L","Sankoh O","Nonterah EA","Mashinya F","Ali SA"],"additional_accession":[]},"is_claimable":false,"name":"Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study.","description":"There is an alarming tide of cardiovascular and metabolic disease (CMD) sweeping across Africa. This may be a result of an increasingly urbanized lifestyle characterized by the growing consumption of processed and calorie-dense food, combined with physical inactivity and more sedentary behaviour. While the link between lifestyle and public health has been extensively studied in Caucasian and African American populations, few studies have been conducted in Africa. This paper describes the detailed methods for Phase 1 of the AWI-Gen study that were used to capture phenotype data and assess the associated risk factors and end points for CMD in persons over the age of 40 years in sub-Saharan Africa (SSA). We developed a population-based cross-sectional study of disease burden and phenotype in ","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2025-04-21T18:16:40.668Z","creation":"2019-03-26T23:58:31Z"},"accession":"S-EPMC6161608","cross_references":{"pubmed":["30259792"],"doi":["10.1080/16549716.2018.1507133"]}}