{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jang CE"],"funding":["NIEHS NIH HHS","Ministry of Health and Welfare"],"pagination":["526"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6162932"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, enduring, and sometimes irreversible neurotoxic symptom that occurs in 30-40% of chemotherapy-treated cancer patients. CIPN negatively affects both the patient's abilities to perform daily activities and their health-related quality of life (HRQOL) after chemotherapy treatment. Although this neuropathy has been treated with duloxetine and/or gabapentin, limited therapeutic benefits have been reported, thereby necessitating the development of an integrated approach that combines pharmacological management and complementary methods such as acupuncture and electric nerve stimulation. Therefore, this study is designed to examine the effect of a portable, low-frequency electrostimulation (ES) device on CIPN s"],"journal":["Trials"],"pubmed_title":["The evaluation of changes in peripheral neuropathy and quality-of-life using low-frequency electrostimulation in patients treated with chemotherapy for breast cancer: a study protocol."],"pmcid":["PMC6162932"],"funding_grant_id":["HI15C0007","27398C0007"],"pubmed_authors":["Lee JS","Jang CE","Jung MS","Sohn EH","Yoo HS","Kim JR","Kim M","Bae K"],"additional_accession":[]},"is_claimable":false,"name":"The evaluation of changes in peripheral neuropathy and quality-of-life using low-frequency electrostimulation in patients treated with chemotherapy for breast cancer: a study protocol.","description":"<h4>Background</h4>Chemotherapy-induced peripheral neuropathy (CIPN) is a progressive, enduring, and sometimes irreversible neurotoxic symptom that occurs in 30-40% of chemotherapy-treated cancer patients. CIPN negatively affects both the patient's abilities to perform daily activities and their health-related quality of life (HRQOL) after chemotherapy treatment. Although this neuropathy has been treated with duloxetine and/or gabapentin, limited therapeutic benefits have been reported, thereby necessitating the development of an integrated approach that combines pharmacological management and complementary methods such as acupuncture and electric nerve stimulation. Therefore, this study is designed to examine the effect of a portable, low-frequency electrostimulation (ES) device on CIPN s","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Sep","modification":"2026-06-13T04:05:24.754Z","creation":"2026-06-13T03:12:39.124Z"},"accession":"S-EPMC6162932","cross_references":{"pubmed":["30268158"],"doi":["10.1186/s13063-018-2874-2"]}}