{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(1)"],"submitter":["Hammoudi N"],"pubmed_abstract":["Studies of tissue regeneration and host-pathogen interactions using the model planarian Schmidtea mediterranea have been performed at an experimental temperature of 19 °C. S. mediterranea planarians exposed to 19 °C-32 °C were observed for survival, mobility, feeding and regeneration for three months and elimination of the Staphylococcus aureus pathogen over six days. S. mediterranea planarians died at 30 °C-32 °C after 18 days of observation but tolerated temperatures of 19 °C up to 28 °C with non-significant differences in mobility and feeding behavior. Genetic malleability tested by RNAi feeding was still efficient at 26 °C and 28 °C. Concerning the immune capacity of planarians, we reported an exacerbation of the immune response in worms infected by S. aureus at 26 °C and 28 °C. These "],"journal":["Scientific reports"],"pagination":["14934"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6175859"],"repository":["biostudies-literature"],"pubmed_title":["Temperature affects the biology of Schmidtea mediterranea."],"pmcid":["PMC6175859"],"pubmed_authors":["Drancourt M","Hammoudi N","Torre C","Ghigo E"],"additional_accession":[]},"is_claimable":false,"name":"Temperature affects the biology of Schmidtea mediterranea.","description":"Studies of tissue regeneration and host-pathogen interactions using the model planarian Schmidtea mediterranea have been performed at an experimental temperature of 19 °C. S. mediterranea planarians exposed to 19 °C-32 °C were observed for survival, mobility, feeding and regeneration for three months and elimination of the Staphylococcus aureus pathogen over six days. S. mediterranea planarians died at 30 °C-32 °C after 18 days of observation but tolerated temperatures of 19 °C up to 28 °C with non-significant differences in mobility and feeding behavior. Genetic malleability tested by RNAi feeding was still efficient at 26 °C and 28 °C. Concerning the immune capacity of planarians, we reported an exacerbation of the immune response in worms infected by S. aureus at 26 °C and 28 °C. These ","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Oct","modification":"2026-05-06T06:49:08.226Z","creation":"2019-03-27T00:02:21Z"},"accession":"S-EPMC6175859","cross_references":{"pubmed":["30297872"],"doi":["10.1038/s41598-018-33355-5"]}}