{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hoppe S"],"funding":["Deutsche Forschungsgemeinschaft"],"pagination":["719"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6182809"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(1)"],"pubmed_abstract":["<h4>Objective</h4>Chloride (Cl<sup>-</sup>) secretion is crucial for intestinal fluid secretion. Therefore, effects of the polyphenol Resveratrol (RSV) on Cl<sup>-</sup> secretion have been investigated. In a previous study, we observed effects of RSV on forskolin-induced Cl<sup>-</sup> secretion in the porcine jejunum but not the ileum although RSV itself induced a transepithelial ion current that may represent Cl<sup>-</sup> secretion in the ileum. The aim of this study was to gain further insights regarding the effects of RSV on characteristics of Cl<sup>-</sup> secretion in the porcine ileum using the Ussing chamber technique (recording of short circuit currents (I<sub>sc</sub>) as a measure for epithelial net ion transfer).<h4>Results</h4>RSV increased the I<sub>sc</sub> in the porcin"],"journal":["BMC research notes"],"pubmed_title":["Calcium-induced chloride secretion is decreased by Resveratrol in ileal porcine tissue."],"pmcid":["PMC6182809"],"funding_grant_id":["KL 2882/2-1"],"pubmed_authors":["Hoppe S","Klinger S","Breves G"],"additional_accession":[]},"is_claimable":false,"name":"Calcium-induced chloride secretion is decreased by Resveratrol in ileal porcine tissue.","description":"<h4>Objective</h4>Chloride (Cl<sup>-</sup>) secretion is crucial for intestinal fluid secretion. Therefore, effects of the polyphenol Resveratrol (RSV) on Cl<sup>-</sup> secretion have been investigated. In a previous study, we observed effects of RSV on forskolin-induced Cl<sup>-</sup> secretion in the porcine jejunum but not the ileum although RSV itself induced a transepithelial ion current that may represent Cl<sup>-</sup> secretion in the ileum. The aim of this study was to gain further insights regarding the effects of RSV on characteristics of Cl<sup>-</sup> secretion in the porcine ileum using the Ussing chamber technique (recording of short circuit currents (I<sub>sc</sub>) as a measure for epithelial net ion transfer).<h4>Results</h4>RSV increased the I<sub>sc</sub> in the porcin","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Oct","modification":"2025-04-22T06:45:28.411Z","creation":"2019-03-27T00:02:43Z"},"accession":"S-EPMC6182809","cross_references":{"pubmed":["30309374"],"doi":["10.1186/s13104-018-3825-4"]}}