{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Abecia L"],"funding":["Biotechnology and Biological Sciences Research Council","Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria"],"pagination":["2227"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6189281"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["This work aimed to gain insight into the transition from milk to solid feeding at weaning combining genomics and metabolomics on rumen contents from goat kids treated with a methanogenic inhibitor (bromochloromethane, BCM). Sixteen goats giving birth to two kids were used. Eight does were treated (D+) with BCM after giving birth and over 2 months. One kid per doe in both groups was treated with BCM (k+) for 3 months while the other was untreated (k-). Rumen samples were collected from kids at weaning (W) and 1 (W + 1) and 4 (W + 4) months after and from does at weaning and subjected to 16S pyrosequencing and metabolomics analyses combining GC/LC-MS. Results from pyrosequencing showed a clear effect of age of kids, with more diverse bacterial community as solid feed becomes more important a"],"journal":["Frontiers in microbiology"],"pubmed_title":["Analysis of the Rumen Microbiome and Metabolome to Study the Effect of an Antimethanogenic Treatment Applied in Early Life of Kid Goats."],"pmcid":["PMC6189281"],"funding_grant_id":["BBS/E/W/10964A01B","BBS/OS/GC/000011B"],"pubmed_authors":["Martin-Garcia AI","Martinez-Fernandez G","Waddams K","Pinloche E","Newbold CJ","Yanez-Ruiz DR","Creevey CJ","Denman SE","Abecia L"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of the Rumen Microbiome and Metabolome to Study the Effect of an Antimethanogenic Treatment Applied in Early Life of Kid Goats.","description":"This work aimed to gain insight into the transition from milk to solid feeding at weaning combining genomics and metabolomics on rumen contents from goat kids treated with a methanogenic inhibitor (bromochloromethane, BCM). Sixteen goats giving birth to two kids were used. Eight does were treated (D+) with BCM after giving birth and over 2 months. One kid per doe in both groups was treated with BCM (k+) for 3 months while the other was untreated (k-). Rumen samples were collected from kids at weaning (W) and 1 (W + 1) and 4 (W + 4) months after and from does at weaning and subjected to 16S pyrosequencing and metabolomics analyses combining GC/LC-MS. Results from pyrosequencing showed a clear effect of age of kids, with more diverse bacterial community as solid feed becomes more important a","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-05-01T01:44:15.557Z","creation":"2019-03-27T00:03:56Z"},"accession":"S-EPMC6189281","cross_references":{"pubmed":["30356690"],"doi":["10.3389/fmicb.2018.02227"]}}