{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ijaz UZ"],"funding":["Natural Environment Research Council","Biotechnology and Biological Sciences Research Council"],"pagination":["2452"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6196313"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["Chickens are a key food source for humans yet their microbiome contains bacteria that can be pathogenic to humans, and indeed potentially to chickens themselves. <i>Campylobacter</i> is present within the chicken gut and is the leading cause of bacterial foodborne gastroenteritis within humans worldwide. Infection can lead to secondary sequelae such as Guillain-Barré syndrome and stunted growth in children from low-resource areas. Despite the global health impact and economic burden of <i>Campylobacter</i>, how and when <i>Campylobacter</i> appears within chickens remains unclear. The lack of day to day microbiome data with replicates, relevant metadata, and a lack of natural infection studies have delayed our understanding of the chicken gut microbiome and <i>Campylobacter</i>. Here, we p"],"journal":["Frontiers in microbiology"],"pubmed_title":["Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for <i>Campylobacter</i>."],"pmcid":["PMC6196313"],"funding_grant_id":["NE/L011956/1","BBS/E/F/000PR10349"],"pubmed_authors":["Gundogdu O","Elmi A","Sivaloganathan L","Dorrell N","McKenna A","Richmond A","Kelly C","Corcionivoschi N","Lavery U","Stratakos AC","Wren BW","Ijaz UZ","Linton M"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for <i>Campylobacter</i>.","description":"Chickens are a key food source for humans yet their microbiome contains bacteria that can be pathogenic to humans, and indeed potentially to chickens themselves. <i>Campylobacter</i> is present within the chicken gut and is the leading cause of bacterial foodborne gastroenteritis within humans worldwide. Infection can lead to secondary sequelae such as Guillain-Barré syndrome and stunted growth in children from low-resource areas. Despite the global health impact and economic burden of <i>Campylobacter</i>, how and when <i>Campylobacter</i> appears within chickens remains unclear. The lack of day to day microbiome data with replicates, relevant metadata, and a lack of natural infection studies have delayed our understanding of the chicken gut microbiome and <i>Campylobacter</i>. Here, we p","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018","modification":"2026-04-07T15:55:33.18Z","creation":"2019-03-27T00:05:20Z"},"accession":"S-EPMC6196313","cross_references":{"pubmed":["30374341"],"doi":["10.3389/fmicb.2018.02452"]}}