{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li J"],"funding":["Capital Health Research and Development of Special","Intramural CDC HHS"],"pagination":["89-91"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC6198331"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["75"],"pubmed_abstract":["Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated with PCF. This article reports an outbreak of PCF that involved 55 students and staff at a university in Beijing, China. Fifty patients had used the same swimming pool 2 weeks before the onset of symptoms. HAdV type 4 was identified from patient eye and throat swabs and concentrated swimming pool water samples. Partial hexon gene sequences obtained from the water samples were 100% identical to the sequences obtained from the swab samples, which clustered with HAdV-4 within species E. Swimming pool water contaminated with HAdV-4 was the most likely source of infection, although one instance of likely person-to-person transmission was noted."],"journal":["International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases"],"pubmed_title":["A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China."],"pmcid":["PMC6198331"],"funding_grant_id":["CC999999","2014-1-1011"],"pubmed_authors":["Li J","Yang Y","Lin C","Wang Q","Lu X","Li F","Liang Z","Chen L","Jiang B","Sun Y","Jia L"],"additional_accession":[]},"is_claimable":false,"name":"A swimming pool-associated outbreak of pharyngoconjunctival fever caused by human adenovirus type 4 in Beijing, China.","description":"Patients with swimming pool-acquired human adenovirus (HAdV) infections usually manifest characteristic clinical features that include fever, pharyngitis, and conjunctival inflammation, syndromically referred to as pharyngoconjunctival fever (PCF). HAdV types 3, 4, and 7 are most commonly associated with PCF. This article reports an outbreak of PCF that involved 55 students and staff at a university in Beijing, China. Fifty patients had used the same swimming pool 2 weeks before the onset of symptoms. HAdV type 4 was identified from patient eye and throat swabs and concentrated swimming pool water samples. Partial hexon gene sequences obtained from the water samples were 100% identical to the sequences obtained from the swab samples, which clustered with HAdV-4 within species E. Swimming pool water contaminated with HAdV-4 was the most likely source of infection, although one instance of likely person-to-person transmission was noted.","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Oct","modification":"2024-12-04T05:59:05.948Z","creation":"2019-03-27T00:04:16Z"},"accession":"S-EPMC6198331","cross_references":{"pubmed":["30144556"],"doi":["10.1016/j.ijid.2018.08.009"]}}