biostudies-literatureWei BResearch of Animal and Plant Quarantine AgencyKorea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and FisheriesBasic Science Research Program through the NRFe0205324https://www.ebi.ac.uk/biostudies/studies/S-EPMC6200224biostudies-literatureUnknown13(10)Culture-based detection of Campylobacter can be affected by competing flora, temperature, incubation time, and presence of blood. The presence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in poultry has become one of the most common factors interfering with the detection of Campylobacter. In the present study, we evaluated potassium clavulanate (ESBL inhibitor) as a supplement in Bolton broth (C-Bolton broth) for enrichment and detection of Campylobacter. First, we determined growth kinetics of Campylobacter in the presence of different concentrations of ESBL E. coli in C-Bolton broth during enrichment. The effects of other factors such as incubation time, incubation temperature, and presence of blood on Campylobacter detection in C-Bolton broth were also investigatedPloS oneEvaluation of potassium clavulanate supplementation of Bolton broth for enrichment and detection of Campylobacter from chicken.PMC6200224716002-7Z-1543073-2015-16-012017R1D1A1B03030883Jang HKWei BKang MfalseEvaluation of potassium clavulanate supplementation of Bolton broth for enrichment and detection of Campylobacter from chicken.Culture-based detection of Campylobacter can be affected by competing flora, temperature, incubation time, and presence of blood. The presence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in poultry has become one of the most common factors interfering with the detection of Campylobacter. In the present study, we evaluated potassium clavulanate (ESBL inhibitor) as a supplement in Bolton broth (C-Bolton broth) for enrichment and detection of Campylobacter. First, we determined growth kinetics of Campylobacter in the presence of different concentrations of ESBL E. coli in C-Bolton broth during enrichment. The effects of other factors such as incubation time, incubation temperature, and presence of blood on Campylobacter detection in C-Bolton broth were also investigated2018-01-01T00:00:00Z20182025-05-29T19:02:51.073Z2019-03-27T00:08:08ZS-EPMC62002243035629610.1371/journal.pone.0205324